author = {Sachdev, Mahipal. and Kumar, Harsh. and Jain, A. and Goulatia, R. and Misra, N.}, title = {{Transsynaptic neuronal degeneration of optic nerves associated with bilateral occipital lesions}}, journal ={Indian Journal of Ophthalmology}, volume ={38}, number ={4}, pages = {151-152}, year = {1990}, abstract ={A case is reported of a 9-year old male who presented with abnormal behaviour and progressive diminution of vision. Pupils were middilated in both eyes but the pupillary reflexes were preserved. Fundus examination revealed a bilateral optic atrophy and radiological investigations showed a bilateral occipital calcification. We hereby document a case of retrograde transsynaptic neuronal degeneration of the visual system secondary to bilateral occipital lesions. Transsynapptic neuronal degeneration of optic nerves consequent to occipital lobe lesions is a rare phenomenon. Experimentally occipital lobe ablation in non-human primates has been shown to result in optic atrophy. Herein, we document a case of retrograde transsynaptic neuronal degeneration of the visual system secondary to bilateral occipital lesions.}, URL ={https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=1990;volume=38;issue=4;spage=151;epage=152;aulast=Sachdev;t=6}, eprint ={https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=1990;volume=38;issue=4;spage=151;epage=152;aulast=Sachdev;t=6} }