TY - JOUR
A1 - Singh, Vijay
A1 - Tripathi, P
T1 - Gene therapy in ocular diseases
Y1 - 2002/7/1
JF - Indian Journal of Ophthalmology
JO - Indian J Ophthalmol
SP - 173
EP - 181
VL - 50
IS - 3
UR - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2002;volume=50;issue=3;spage=173;epage=181;aulast=Singh
N2 - Gene therapy is a novel form of drug delivery that enlists the synthetic machinery of the patient's cells to produce a therapeutic agent. Genes may be delivered into cells in vitro or in vivo utilising viral or non-viral vectors. Recent technical advances have led to the demonstration of the molecular basis of various ocular diseases. Ocular disorders with the greatest potential for benefit of gene therapy include hereditary diseases such as retinitis pigmentosa, tumours such as retinoblastoma or melanoma, and acquired proliferative and neovascular retinal disorders. Gene transfer into ocular tissues has been demonstrated with growing functional success and may develop into a new therapeutic tool for clinical ophthalmology in future.
ER -