TY - JOUR A1 - Kaul, Shalini A1 - Uparkar, Mahesh A1 - Mody, Kruti A1 - Walinjkar, Jaydeep A1 - Kothari, Mihir A1 - Natarajan, S T1 - Intravitreal anti-vascular endothelial growth factor agents as an adjunct in the management of Coats' disease in children Y1 - 2010/1/1 JF - Indian Journal of Ophthalmology JO - Indian J Ophthalmol SP - 76 EP - 78 VL - 58 IS - 1 UR - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2010;volume=58;issue=1;spage=76;epage=78;aulast=Kaul DO - 10.4103/0301-4738.58480 N2 - We describe the role of intravitreal anti-vascular endothelial growth factor (VEGF) agents in Coats' disease in children. In a prospective, interventional, non-randomized case series, three patients (three eyes) aged 16, seven and two years were diagnosed to have Coats' disease. In Case 1 (16 yr/ male) with macular edema, previous laser photocoagulation being unsuccessful, intravitreal pegaptanib sodium (Macugen™) was tried. Case 2 (seven yr/ male) and Case 3 (two yr/ female) were diagnosed to have Stage 4 Coats' and underwent external needle drainage, laser photocoagulation, SF6 gas injection and intravitreal injection of bevacizumab (Avastin™). Reduction of exudation and attached posterior pole (Cases 2 and 3) was seen at a follow-up of six months and two months respectively. Intravitreal anti-VEGF agents may be successfully used as adjunct treatment in select cases of Coats' disease in childhood. ER -