AU - Chhablani, Preeti AU - Kekunnaya, Ramesh TI - Neuro-ophthalmic manifestations of prematurity PT - REVI DP - 2014 Oct 1 TA - Indian Journal of Ophthalmology PG - 992-995 VI - 62 IP - 10 4099- https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2014;volume=62;issue=10;spage=992;epage=995;aulast=Chhablani;type=0 4100- https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2014;volume=62;issue=10;spage=992;epage=995;aulast=Chhablani AB - Increasing rates of preterm births coupled with better survival of these infants have resulted in higher prevalence of systemic and ocular complications associated with prematurity. In addition to retinopathy of prematurity, infants who are born preterm may suffer from severe visual impairment as a result of hypoxic ischemic encephalopathy, hypoglycemia, and other metabolic imbalances. The effect of these processes on the anterior visual pathway may result in optic atrophy, optic nerve hypoplasia or optic disc cupping and affection of the posterior visual pathway leads to cortical visual impairment (CVI). Other ocular associations include strabismus, nystagmus, and ocular motor abnormalities such as tonic down gaze and defective saccades and pursuits. Cortical and subcortical involvement also manifests as defects in functional vision and these have not yet been completely understood. Children with CVI may have visual field defects, photophobia, defective visual processing, and deficient color vision. Since most of these children also suffer from additional systemic disabilities, evaluation, and management remains a challenge. However, early diagnosis and initiation of rehabilitation therapy can prove to be of significant benefit in these children.