TY - JOUR A1 - Shanmugam, P A1 - Barigali, Aditya A1 - Kadaskar, Jayant A1 - Borgohain, Sandip A1 - Mishra, Divaynsh A1 - Ramanjulu, Rajesh A1 - Minija, C T1 - Effect of lanosterol on human cataract nucleus Y1 - 2015//1 JF - Indian Journal of Ophthalmology JO - Indian J Ophthalmol SP - 888 EP - 890 VL - 63 IS - 12 UR - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2015;volume=63;issue=12;spage=888;epage=890;aulast=Shanmugam DO - 10.4103/0301-4738.176040 N2 - Aim: To study the effect of lanosterol on age-related cataractous human lens nuclei. Materials and Methods: Forty age-related cataractous nuclei removed during manual small incision cataract surgery were obtained and randomly immersed in 25 mM lanosterol solution or in control solution and stored at room temperature for 6 days. Pre- and post-immersion photographs were graded by two masked observers and collated for the regression or progression of lens opacity. Results: Both lanosterol and control groups showed progression or no change in the lens opacity at the end of 6 days. Conclusion: Lanosterol 25 mM solution did not reverse opacification of human age-related cataractous nuclei. ER -