RT - Journal TY - JOUR A1 - Nair, Akshay A1 - Jain, Vandana A1 - Gopinathan, Indumati A1 - Murthy, Anuradha T1 - Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual site YR - 2016/6/1 JF - Indian Journal of Ophthalmology JO - Indian J Ophthalmol SP - 466 OP - 468 VO - 64 IS - 6 UL - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2016;volume=64;issue=6;spage=466;epage=468;aulast=Nair;t=5 DO - 10.4103/0301-4738.187680 N2 - We describe the clinicopathological features of a solid variant of orbital angioleiomyoma. A review of clinical records, diagnostic, and radiographic studies combined with histopathological evaluation with standard histochemical staining and immunohistochemistry was conducted. A 22-year-old male patient presented with a mass in the region of the left lacrimal gland that was gradually increasing over the past 2 years. Radiological and clinical examinations showed no signs suspicious of a malignancy and fine needle aspiration cytology was inconclusive. Therefore, an excision biopsy was performed. On histopathological examination, the picture was consistent with a benign spindle cell tumor. Immunohistochemistry showed positivity for CD 34 and CD 31 (markers for vascular endothelium). The tumor also showed positivity for smooth muscle actin and Ki-67 proliferative index was low. Angioleiomyomas are rarely encountered in the orbit and has features seen in leiomyoma as well as some vascular tumor elements. In most cases, surgical excision is usually curative. ER -