RT - Journal TY - JOUR A1 - Foroutan, Alireza A1 - Ghafourian, Abdolhossein A1 - Habibi, Abbas A1 - Foroutan, Pooria A1 - Ashrafkhorasani, Maryam A1 - Alemzadeh, Sayyed T1 - Successful treatment of allergic conjunctival granuloma by topical tacrolimus: A clinicopathologic case report YR - 2018/4/1 JF - Indian Journal of Ophthalmology JO - Indian J Ophthalmol SP - 578 OP - 580 VO - 66 IS - 4 UL - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2018;volume=66;issue=4;spage=578;epage=580;aulast=Foroutan;t=5 DO - 10.4103/ijo.IJO_490_16 N2 - Allergic conjunctival granuloma is a rare cause of conjunctival ocular lesions. The aim of this case report was to present a successful treatment of an allergic conjunctival granuloma with topical tacrolimus eye drops. A 20-year-old female presented with bilateral multiple yellow nodules of the bulbar conjunctival epithelium and conjunctival injection. The patient had tearing, photophobia, itching, foreign body sensation, and red eye. The patient's signs and symptoms progressed despite the use of topical steroids. The patient was treated by application of tacrolimus eye drop (0.005%) in her right eye every 6 h while the left eye was put on placebo. Her signs and symptoms were recorded at each visit. After 3 weeks' therapy with topical tacrolimus eye drop, the patient became asymptomatic in her right eye and conjunctival granulomas fully resolved. Topical tacrolimus seems to be an effective therapeutic option for the treatment of allergic conjunctival granulomas. ER -