Indian Journal of Ophthalmology

ORIGINAL ARTICLE
Year
: 1994  |  Volume : 42  |  Issue : 2  |  Page : 71--74

Donor corneoscleral rim contamination by gentamicin-resistant organisms


Usha Gopinathan1, Vinay Agrawal2, Savitri Sharma1, Gullapalli N Rao3 
1 Sri Devchand Nagardas Jhaveri Microbiology Centre, Hyderabad, India
2 Sight Savers' Cornea Training Centre, L.V. Prasad Eye Institute, Hyderabad 500 034, India
3 Sri Devchand Nagardas Jhaveri Microbiology Centre,& Sight Savers Cornea Training Centre, L.V. Prasad Eye Institute, Hyderabad 500 034, India

Correspondence Address:
Savitri Sharma
L.V. Prasad Eye Institute, Road No. 2, Banjara Hills, Hyderabad 500 034
India

Gentamicin is the most widely used antibiotic in the decontamination of donor cornea for penetrating keratoplasty. However, the incidence of resistance to gentamicin is on the rise. Bacterial isolates from 178 donor corneal rims were studied for gentamicin sensitivity. The overall rate of gentamicin resistance was 63.4%. At 86.2% the Pseudomonas. species had the highest rate of resistance, followed by Streptococci at 84.6%. The high rate of gentamicin resistance encountered by us and others suggest that either addition of a second antibiotic to corneal storage media or replacement of gentamicin by an antibiotic with a broader spectrum of activity may help reduce the risk of endophthalmitis following penetrating keratoplasty


How to cite this article:
Gopinathan U, Agrawal V, Sharma S, Rao GN. Donor corneoscleral rim contamination by gentamicin-resistant organisms.Indian J Ophthalmol 1994;42:71-74


How to cite this URL:
Gopinathan U, Agrawal V, Sharma S, Rao GN. Donor corneoscleral rim contamination by gentamicin-resistant organisms. Indian J Ophthalmol [serial online] 1994 [cited 2020 Aug 14 ];42:71-74
Available from: http://www.ijo.in/article.asp?issn=0301-4738;year=1994;volume=42;issue=2;spage=71;epage=74;aulast=Gopinathan;type=0