Indian Journal of Ophthalmology

ORIGINAL ARTICLE
Year
: 1997  |  Volume : 45  |  Issue : 4  |  Page : 227--231

Possible role of lens collagen in cataractogenesis


G Mishra, GB Das, HN Behera 
 P.G. Department of Zoology, Berhampur University, India

Correspondence Address:
G Mishra
P.G. Department of Zoology, Berhampur University
India

The solubility characteristics of collagen in human cataractous eye lenses were studied in relation to age. Post-operative cataractous lenses were collected form eye camps in Phulbani district of Orissa. These were preserved in 70 % alcohol and immediately transferred to the laboratory. Various fractions in the collagen obtained from lens capsule of each lens sample were estimated. The salt-soluble and the acid-soluble collagens showed positive correlation with age. The insoluble and total capsular collagen increased with increasing age. The solubility percentage of collagen in salt and acid solutions decreased significantly with increasing age. The possible role of lens collagen in the development of cataract with increasing age is discussed in the background of cross-link theory of aging.


How to cite this article:
Mishra G, Das G B, Behera H N. Possible role of lens collagen in cataractogenesis.Indian J Ophthalmol 1997;45:227-231


How to cite this URL:
Mishra G, Das G B, Behera H N. Possible role of lens collagen in cataractogenesis. Indian J Ophthalmol [serial online] 1997 [cited 2024 Mar 29 ];45:227-231
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