Indian Journal of Ophthalmology

ORIGINAL ARTICLE
Year
: 2003  |  Volume : 51  |  Issue : 4  |  Page : 315--321

Epidemiological characteristics and laboratory diagnosis of fungal keratitis. A three-year study


M Jayahar Bharathi, R Ramakrishnan, S Vasu, R Meenakshi, R Palaniappan 
 Department of Microbiology, Aravind Eye Care System, Tirunelveli, Tamil Nadu, India

Correspondence Address:
M Jayahar Bharathi
Department of Microbiology, Aravind Eye Care System, Tirunelveli, Tamil Nadu
India

Purpose: To study the epidemiological characteristics and laboratory diagnosis of fungal keratitis seen at a tertiary eye care referral centre in South India. Methods: A retrospective review of all culture-proven fungal keratitis seen over a 3-year period, September 1999 through August 2002. Results: Fungal aetiology were confirmed in1095(34.4%) of 3183 corneal ulcers. The predominant fungal species isolated was Fusarium spp (471; 42.82%) followed by Aspergillus spp (286; 26%). Males (712; 65.08%) were more often affected (P< 0.0001). A large proportion of the patients (732; 66.85%) were in the younger age group (21 to 50 years). A majority (879; 80.27%) came from rural areas (P<0.0001), and most patients (709; 64.75%) were farmers (P<0.0001). Ocular trauma (1009; 92.15%) was a highly significant risk factor (P<0.0001) and vegetative injuries (671; 61.28%) were identified as a significant cause for fungal keratitis (P<0.0001). 172 (15.71%) patients had concurrent diabetes mellitus. The sensitivity of 10% potassium hydroxide (KOH) wet mount preparation was higher (99.23%) than Gram-stained smear (88.73%) (P<0.0001). Incidence of fungal keratitis was higher between June and September. Conclusion: Agricultural activity and related ocular trauma were principal causes of mycotic keratitis. A potassium hydroxide (KOH) wet mount preparation is a simple, and sensitive, method for diagnosis.


How to cite this article:
Bharathi M J, Ramakrishnan R, Vasu S, Meenakshi R, Palaniappan R. Epidemiological characteristics and laboratory diagnosis of fungal keratitis. A three-year study.Indian J Ophthalmol 2003;51:315-321


How to cite this URL:
Bharathi M J, Ramakrishnan R, Vasu S, Meenakshi R, Palaniappan R. Epidemiological characteristics and laboratory diagnosis of fungal keratitis. A three-year study. Indian J Ophthalmol [serial online] 2003 [cited 2019 Nov 18 ];51:315-321
Available from: http://www.ijo.in/article.asp?issn=0301-4738;year=2003;volume=51;issue=4;spage=315;epage=321;aulast=Bharathi;type=0