Indian Journal of Ophthalmology

BRIEF COMMUNICATION
Year
: 2008  |  Volume : 56  |  Issue : 2  |  Page : 161--162

A case of neurofibromatosis 1 presenting with optic pathway glioma with an early onset and an aggressive course


Suma Ganesh, Archana Gupta, Manish Sharma, Sandeep Bhuttan 
 Pediatric Ophthalomology Department, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India

Correspondence Address:
Suma Ganesh
Dr. Shroff«SQ»s Charity Eye Hospital, Kedarnath Road, Daryaganj, New Delhi - 110 002
India

Optic pathway glioma associated with neurofibromatosis 1 has a classically indolent course. However, involvement of the optic radiations is relatively rare and is associated with a more aggressive course. A three-year-old girl presented with strabismus and loss of vision in the left eye with relative afferent pupillary defect and optic disc pallor. She had multiple cafι au lait spots. Visually evoked potential was suggestive of an optic nerve conduction defect and magnetic resonance imaging of the brain was suggestive of an optic pathway glioma involving the optic nerves, the optic chiasma and the optic tracts. The optic radiations and the dentate nuclei had hamartomas. Optic nerve biopsy confirmed pilocytic astrocytoma. Radical radiotherapy under general anesthesia was subsequently given. This case report aims to highlight the involvement of the optic radiations and the unusually aggressive clinical course in this case.


How to cite this article:
Ganesh S, Gupta A, Sharma M, Bhuttan S. A case of neurofibromatosis 1 presenting with optic pathway glioma with an early onset and an aggressive course.Indian J Ophthalmol 2008;56:161-162


How to cite this URL:
Ganesh S, Gupta A, Sharma M, Bhuttan S. A case of neurofibromatosis 1 presenting with optic pathway glioma with an early onset and an aggressive course. Indian J Ophthalmol [serial online] 2008 [cited 2020 Jul 2 ];56:161-162
Available from: http://www.ijo.in/article.asp?issn=0301-4738;year=2008;volume=56;issue=2;spage=161;epage=162;aulast=Ganesh;type=0