Indian Journal of Ophthalmology

SYMPOSIUM
Year
: 2011  |  Volume : 59  |  Issue : 2  |  Page : 117--122

Management of optic neuritis


Vimla Menon, Rohit Saxena, Ruby Misra, Swati Phuljhele 
 Dr. R. P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Rohit Saxena
Squint and Neuro-Ophthalmology Section, Dr. R. P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi - 110 029
India

Optic neuritis is an inflammatory condition of the optic nerve characterized by a sudden onset of unilateral visual loss, usually affecting young females. Demyelination associated with multiple sclerosis (MS) is the most common cause in regions where MS is prevalent; while in other places, there are a substantial proportion of cases where infective or autoimmune causes are seen. Optic Neuritis Treatment Trial (ONTT) was the first major study that provided information on the natural history, role of steroids in treatment and risk of development of MS. Subsequently, numerous clinical trials have evaluated different modalities of management of optic neuritis and MS. The Controlled High-Risk Subjects Avonex Multiple Sclerosis Prevention Study (CHAMPS); the Prevention of Relapses and Disability by Interferon β-1a Subcutaneously in Multiple Sclerosis (PRISMS) Trial; and, most recently, the Betaferon in Newly Emerging Multiple Sclerosis for Initial Treatment (BENEFIT) Study have provided large amount of information on the natural history of optic neuritis and management options available. However, due to the low prevalence of MS reported in Asian studies, high cost of therapy and indefinite time period of treatment, it may not be cost effective to start interferon therapy in most cases.


How to cite this article:
Menon V, Saxena R, Misra R, Phuljhele S. Management of optic neuritis.Indian J Ophthalmol 2011;59:117-122


How to cite this URL:
Menon V, Saxena R, Misra R, Phuljhele S. Management of optic neuritis. Indian J Ophthalmol [serial online] 2011 [cited 2024 Mar 29 ];59:117-122
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