Indian Journal of Ophthalmology

REVIEW ARTICLE
Year
: 2014  |  Volume : 62  |  Issue : 7  |  Page : 768--772

Nanostructure-based platforms-current prospective in ophthalmic drug delivery


Rakesh Kumar Sharma, Alaa Eldeen B Yassin 
 Department of Pharmaceutics, College of Pharmacy, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia

Correspondence Address:
Rakesh Kumar Sharma
Department of Pharmaceutics, College of Pharmacy, King Saud Bin Abdulaziz University for Health Sciences, Riyadh
Kingdom of Saudi Arabia

The topically applied drugs as drops are washed off from the eye in very short period, resulting in low ocular bioavailability of drugs. Number of approaches have been attempted to increase the bioavailability and the duration of action of ocular drugs. This review provides an insight into various novel approaches; hydrophilic nanogels, solid lipid nanoparticles, and nanosponges applied very recently in the delivery of insoluble drugs, prolonging the ocular residence time, minimize pre-corneal drug loss and, therefore, bioavailability and therapeutic efficacy of the drugs. Despite various scientific approaches, efficient ocular drug delivery remains a challenge for pharmaceutical scientists.


How to cite this article:
Sharma RK, Yassin AB. Nanostructure-based platforms-current prospective in ophthalmic drug delivery.Indian J Ophthalmol 2014;62:768-772


How to cite this URL:
Sharma RK, Yassin AB. Nanostructure-based platforms-current prospective in ophthalmic drug delivery. Indian J Ophthalmol [serial online] 2014 [cited 2020 Jun 6 ];62:768-772
Available from: http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=7;spage=768;epage=772;aulast=Sharma;type=0