Indian Journal of Ophthalmology

REVIEW ARTICLE
Year
: 2016  |  Volume : 64  |  Issue : 9  |  Page : 628--634

Roles of interleukin-17 in uveitis


Marta Catarina Esteves Guedes1, Luis Miguel Borrego2, Rui Daniel Proença3 
1 Western Lisbon Hospital Center, Egas Moniz Hospital, Lisbon, Portugal
2 Luis Miguel Borrego, CUF Descobertas Hospital, Lisbon, Portugal
3 Coimbra Hospital and Universitary Center, Coimbra, Portugal

Correspondence Address:
Dr. Marta Catarina Esteves Guedes
Western Lisbon Hospital Center, Egas Moniz Hospital, Lisbon
Portugal

Th17 cells, a CD4+ T-cell subset, produce interleukin (IL)-17, a pro-inflammatory cytokine that has been shown to be involved in several forms of infectious and noninfectious uveitis. Here, we explore the roles of this IL in uveitic disorders as well as in experimental autoimmune uveitis, the possible pathogenic implications of several cytokines associated with IL-17 and analyze the current outcomes and goals for drugs aiming for the IL-17 pathway.


How to cite this article:
Guedes MC, Borrego LM, Proença RD. Roles of interleukin-17 in uveitis.Indian J Ophthalmol 2016;64:628-634


How to cite this URL:
Guedes MC, Borrego LM, Proença RD. Roles of interleukin-17 in uveitis. Indian J Ophthalmol [serial online] 2016 [cited 2024 Mar 29 ];64:628-634
Available from: https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2016;volume=64;issue=9;spage=628;epage=634;aulast=Guedes;type=0