LETTER TO THE EDITOR
Year : 2017 | Volume
: 65 | Issue : 11 | Page : 1266-
Reply to Conjunctival leiomyosarcoma: A case report and review of literature
Tania López Montes
Ophthalmology Service, University Hospital of Vigo, Vigo, Spain
Tania López Montes
Ophthalmology Service, Hospital do Meixoeiro, Vigo 36200
|How to cite this article:|
Montes TL. Reply to Conjunctival leiomyosarcoma: A case report and review of literature.Indian J Ophthalmol 2017;65:1266-1266
|How to cite this URL:|
Montes TL. Reply to Conjunctival leiomyosarcoma: A case report and review of literature. Indian J Ophthalmol [serial online] 2017 [cited 2020 Jan 19 ];65:1266-1266
Available from: http://www.ijo.in/text.asp?2017/65/11/1266/218082
I thank the author for the interest shown in our published article and appreciate the new information reported.
In fact, the number of reported cases of smooth muscle tumor (SMT) arising in the setting of human immunodeficiency virus (HIV) infection has been increasing for the last three decades. Coinfection with Epstein-Barr virus (EBV) appears to be a necessary cofactor for the development of these tumors., These EBV-related SMT also were reported in posttransplant immunosuppressed patients and individuals with autoimmune disease or iatrogenic immunosuppression. None of these conditions, including HIV infection, was present in the patient of our case report. Detection of EBV was performed in the tumor tissue with negative results.
Although EBV-SMT affects especially patients who are young, severely immunosuppressed and have multifocal tumors, it is true that EBV-SMT should be included in the differential diagnosis of any SMT occurring in uncommon sites (e.g., conjunctiva). These tumors appear to have a more favorable prognosis than conventional leiomyosarcoma.
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Conflicts of interest
There are no conflicts of interest.
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