Indian Journal of Ophthalmology

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 66  |  Issue : 10  |  Page : 1429--1434

Trabeculectomy with subconjunctival collagen implant in Indian eyes: Long-term results


Kirti Singh, Mainak Bhattacharyya, Ankush Mutreja, Sonal Dangda 
 Guru Nanak Eye Centre, New Delhi, India

Correspondence Address:
Dr. Mainak Bhattacharyya
19/312, Shivam Khand, Vasundhara, Ghaziabad - 201012, Uttar Pradesh
India

Purpose: To report long-term safety and efficacy of trabeculectomy with collagen implant in Indian population. Methods: All cases of trabeculectomy with Ologen® Collagen Matrix implant performed over a 7-year period from May 2008 through April 2015 at a tertiary referral institute were reviewed. A total of 30 eyes of 28 patients were included in the study with two patients undergoing bilateral trabeculectomy. Outcomes measured included intraocular pressure (IOP) control, number of antiglaucoma medications used, bleb morphology, and complications/reoperations. Results: Trabeculectomy resulted in reduction in IOP from 36.46 to 11.65 mm Hg in the immediate postoperative period (day 1), a 68% decrease to 15.18 mm Hg at 84 months (58% decrease). The mean IOP reduction decreased over time from 63% in the first year to 55% after 5 years of follow-up. Fourteen eyes attained a follow-up of 5 years and eight eyes a follow-up of ≥7 years. No sight-threatening complication such as hypotony, bleb leak, and bleb-related endophthalmitis was observed in our series, and only intervention required was 5-fluorouracil needling in one case. Conclusion: Ologen-augmented trabeculectomy is effective in controlling IOP over a long-term follow up from minimal 3 to maximal 7 years. No untoward events jeopardizing bleb safety were noted at any time. This modality is a viable alternative for patients with contraindications to use of antimetabolites.


How to cite this article:
Singh K, Bhattacharyya M, Mutreja A, Dangda S. Trabeculectomy with subconjunctival collagen implant in Indian eyes: Long-term results.Indian J Ophthalmol 2018;66:1429-1434


How to cite this URL:
Singh K, Bhattacharyya M, Mutreja A, Dangda S. Trabeculectomy with subconjunctival collagen implant in Indian eyes: Long-term results. Indian J Ophthalmol [serial online] 2018 [cited 2024 Mar 29 ];66:1429-1434
Available from: https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2018;volume=66;issue=10;spage=1429;epage=1434;aulast=Singh;type=0