Indian Journal of Ophthalmology

OPHTHALMIC IMAGES
Year
: 2018  |  Volume : 66  |  Issue : 11  |  Page : 1623-

Differential corneal involvement in xeroderma pigmentosum


Sunita Chaurasia 
 Cornea and Anterior Segment Services, Tej Kohli Cornea Institute, L. V. Prasad Eye Institute, Hyderabad, Telangana, India

Correspondence Address:
Dr. Sunita Chaurasia
Tej Kohli Cornea Institute, L. V. Prasad Eye Institute, L. V. Prasad Marg, Banjara Hills, Hyderabad - 500 034, Telangana
India




How to cite this article:
Chaurasia S. Differential corneal involvement in xeroderma pigmentosum.Indian J Ophthalmol 2018;66:1623-1623


How to cite this URL:
Chaurasia S. Differential corneal involvement in xeroderma pigmentosum. Indian J Ophthalmol [serial online] 2018 [cited 2024 Mar 29 ];66:1623-1623
Available from: https://journals.lww.com/ijo/pages/default.aspx/text.asp?2018/66/11/1623/244075


Full Text



A 7-year-old girl was brought with an inability to open the eyes in bright light for the past several years. Examination revealed multiple hyperpigmented skin nevi involving the face, neck, arms, and feet suggestive of clinical diagnosis of xeroderma pigmentosum. The child was extremely photophobic. Lid margin was irregular with severe loss of lashes in the lower eyelid of both eyes. Conjunctiva was dry, atrophic, and pigmented. Cornea showed haze, edema, and vascularization. The left eye showed an area of corneal melt and perforation. As seen in both eyes, the upper one-third of the peripheral cornea was relatively unaffected corresponding to the area that is covered by eyelids [Figure 1]. The selective sparing of the superior part of the cornea is explained by the protective effect of the upper eyelid. This clinical observation emphasizes the fact that the corneal changes in xeroderma are secondary to the cumulative effect of exposure of ultraviolet radiation on the affected area. The disabling corneal changes can be prevented if adequate solar protection is emphasized at an early stage of life.{Figure 1}

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.