Indian Journal of Ophthalmology

CASE REPORT
Year
: 2019  |  Volume : 67  |  Issue : 6  |  Page : 967--969

Post-Ranibizumab injection endophthalmitis in aggressive posterior retinopathy of prematurity


Parijat Chandra, Devesh Kumawat, Ruchir Tewari, Suresh Azimeera 
 Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Dr. Parijat Chandra
Room No. 373, Third Floor, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110 029
India

A preterm infant with zone 1 aggressive posterior retinopathy of prematurity developed infectious endophthalmitis after intravitreal injection of ranibizumab. Urgent empirical intravitreal therapy with vancomycin, ceftazidime, and dexamethasone along with intravenous therapy with amikacin and meropenem helped in early resolution. Vascularization/activity of disease subsided on follow-up, media cleared, and laser photocoagulation was completed. Later the disease reactivated, developed vitreous membranes and central retinal traction, for which 25-gauge lens-sparing vitrectomy was performed. Emergent treatment helped in salvaging the eye from both aggressive ROP disease and devastating endophthalmitis. Rationale approach to such a case is being discussed.


How to cite this article:
Chandra P, Kumawat D, Tewari R, Azimeera S. Post-Ranibizumab injection endophthalmitis in aggressive posterior retinopathy of prematurity.Indian J Ophthalmol 2019;67:967-969


How to cite this URL:
Chandra P, Kumawat D, Tewari R, Azimeera S. Post-Ranibizumab injection endophthalmitis in aggressive posterior retinopathy of prematurity. Indian J Ophthalmol [serial online] 2019 [cited 2019 Sep 18 ];67:967-969
Available from: http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=6;spage=967;epage=969;aulast=Chandra;type=0