Indian Journal of Ophthalmology

: 2020  |  Volume : 68  |  Issue : 1  |  Page : 190--191

Inflammatory deposits on the foldable intraocular lens

Amravi Shah, Chetan Rao, Krishna Kumar, Ronnie Jacob George, Parthopratim Dutta Majumder 
 Department of Uvea and Intraocular Inflammation, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Parthopratim Dutta Majumder
Department of Uvea, Sankara Nethralaya, 18, College Road, Nungambakkam, Chennai - 600 006, Tamil Nadu


How to cite this article:
Shah A, Rao C, Kumar K, George RJ, Dutta Majumder P. Inflammatory deposits on the foldable intraocular lens.Indian J Ophthalmol 2020;68:190-191

How to cite this URL:
Shah A, Rao C, Kumar K, George RJ, Dutta Majumder P. Inflammatory deposits on the foldable intraocular lens. Indian J Ophthalmol [serial online] 2020 [cited 2020 Feb 27 ];68:190-191
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Full Text

A 59-year-old female presented with visual acuity of 6/18, N8 in her left eye, 10 years after combined cataract and glaucoma surgery. Slit-lamp examination revealed a quiet eye with multiple deposits on the intraocular lens (IOL) which could not be removed by YAG laser or manual scraping [Figure 1]a. Histopathological evaluation of explanted IOL revealed multiple histiocytes on the optic surface and multinucleated giant cells on the haptic surface [Figure 1]b, [Figure 1]c, [Figure 1]d. Giant cells, visible on slit lamp as sharp, round, or oval spots with or without pigmentation, usually occur within 2 years after implantation.[1]{Figure 1}


The most conspicuous factor in the development of an inflammatory giant cell reaction, after combined cataract and glaucoma surgery, is IOL design whereby silicone plate IOLs show greater reaction compared with 3-piece acrylic IOLs.[2] Increased intraoperative manipulation involved in combined surgery is responsible for these inflammatory deposits, hence the choice of IOL becomes extremely important in such cases. IOL removal is imperative when they become visually significant.

Declaration of patient consent

A written informed consent was taken from the patient. Ethics committee approval was obtained.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.


1Wolter JR. Foreign body giant cells on intraocular lens implants. Graefes Arch Clin Exp Ophthalmol Albrecht Von Graefes Arch Klin Exp Ophthalmol 1982;219:103-11.
2Samuelson TW, Chu YR, Krieger RA. Evaluation of giant-cell deposits on foldable intraocular lenses after combined cataract and glaucoma surgery. J Cataract Refract Surg 2000;26:817-23.