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   2014| June  | Volume 62 | Issue 6  
    Online since July 8, 2014

 
 
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ORIGINAL ARTICLES
Intraocular lens power calculation in eyes with short axial length
Marilita M Moschos, Irini P Chatziralli, Chryssanthi Koutsandrea
June 2014, 62(6):692-694
DOI:10.4103/0301-4738.129791  PMID:25005197
Aim: To evaluate and compare the predictive capacity of four intraocular lens (IOL) power calculation formulas (SRK/T, Hoffer Q, Holladay 1, and Haigis) in eyes shorter than 22.0 mm. Setting and Design: Observational study. Materials and Methods: Participants in our study were 69 consecutive patients with a preoperative axial length (AL) of less than 22.0 mm in one or both eyes. All patients underwent phacoemulsification with IOL implantation and postoperative target of refraction was analyzed. Specifically, the differences in the mean absolute estimation error (AE) for the four formulas were analyzed. Furthermore, the percentage of eyes with AE within ±0.5 and ±1.0 D for each formula was estimated, as well as the correlation coefficient (r) between the AL and estimation error (E) for each formula. The Mann-Whitney U test was used to compare differences in the AEs of the formulas. A statistically significant difference was defined as P < 0.05. Results: The Haigis formula had statistically significant smaller mean AE in comparison to Holladay 1, Hoffer Q, and SRK/T. The Haigis formula predicted more eyes with E within ±0.5 and ±1.0 D of predicted spherical equivalent compared to other formulas. Correlation between AL and AE revealed a negative r value and P < 0.05 for all formulas. Conclusions: Haigis formula provides more accurate results concerning the postoperative target of refraction in eyes with AL less than 22.0 mm. Hoffer Q could be also used as an alternative.
  5,372 484 -
Morphology of functioning trabeculectomy blebs using anterior segment optical coherence tomography
Mayuri B Khamar, Shruti R Soni, Siddharth V Mehta, Samaresh Srivastava, Viraj A Vasavada
June 2014, 62(6):711-714
DOI:10.4103/0301-4738.136227  PMID:25005200
Purpose: To image trabeculectomy blebs using anterior segment optical coherence tomography (AS-OCT), and to correlate the bleb morphologic features at one month postoperatively with bleb function at six months. Materials and Methods: This prospective, observational study included 56 eyes undergoing trabeculectomy with MMC, followed up for minimum of six months. Postoperatively, bleb imaging was done using AS-OCT at one and six month. Bleb morphology was assessed for bleb wall reflectivity, bleb pattern in multiform reflectivity, visibility of drainage route and presence of hyper-reflectivity area. Bleb function was considered successful if IOP was <18 mmHg without medication at six month. Bleb morphology one month postoperatively was correlated with bleb function at six months. Results: At six months successful bleb function was noted in 44 (81.5%) eyes. Morphology of bleb at one month showed uniform bleb wall reflectivity in 6 eyes (11%) and multiform wall reflectivity in 48 eyes (89%). In eyes with multiform wall reflectivity, microcysts with multiple layers was seen in 26 eyes (48%), microcysts with subconjunctival separation in 12 eyes (22%) and only microcyst in 10 eyes (19%). When bleb features at one month were correlated with the bleb function at six months, logistic regression analysis revealed that blebs with multiform reflectivity with multiple internal layers with microcysts were associated with higher chances of success (P < 0.001). Conclusion : AS-OCT demonstrated early bleb morphological features that may be used to predict the functioning of a bleb. Multiform bleb wall reflectivity with a pattern of multiple internal layers and microcysts was associated with increased chances of success of a bleb.
  3,795 436 -
Comparing measurement techniques of accommodative amplitudes
Hamed Momeni-Moghaddam, James Kundart, Farshad Askarizadeh
June 2014, 62(6):683-687
DOI:10.4103/0301-4738.126990  PMID:25005195
Aim and Background: This study was designed to compare four standard procedures, for determining the monocular accommodative amplitudes. Materials and Methods: Fifty-two students participated in this analytical-descriptive study. Accommodative amplitudes were measured using four common clinical techniques, namely: Push-up, push-down, minus lens, and modified push-up. Results: The highest amplitude was obtained using the push-up method (11.21 ± 1.85 D), while the minus lens technique gave the lowest finding (9.31 ± 1.61 D). A repeated-measures Analysis of Variance (ANOVA) showed a significant difference between these methods (P < 0.05), further analysis showed that this difference was only between the minus lens and other the three methods (the push-up (P < 0.001), the push-down (P < 0.001) and the modified push-up (P < 0.001)). The highest and the lowest mean difference was related to the push-up with the minus lens, and the push-down with the modified push-up, while the highest and the lowest 95% limits of agreement were related to the push-up with the modified push-up and the push-up with the push-down methods. There was almost a perfect agreement between the push-up and the push-down method, whereas, a poor agreement was present between the modified push-up and the minus lens technique, and a fair agreement existed between the other pairs. Conclusions: The quick and easy assessment of the amplitude using the push-up and the push-down methods compared to other methods, and the obtained perfect agreement between these two methods can further emphasize their use as a routine procedure in the clinic, especially if a combination of the two techniques is used to offset their slight over- and underestimation.
  3,472 398 -
A simple modification of the Farnsworth-Munsell 100-Hue test for much faster assessment of color vision
Supriyo Ghose, Dinesh Shrey, Pradeep Venkatesh, Twinkle Parmar, Sourabh Sharma
June 2014, 62(6):721-723
DOI:10.4103/0301-4738.129778  PMID:25005203
Purpose: The Farnsworth-Munsell (FM) 100-hue test is well known but is also time consuming, especially its analytical component. To reduce this needless time-waste during precious working hours, a simple modification was devised. Design: Prospective, comparative, observational study. Materials and Methods: A transparent clear plastic carrier box replaced the opaque one, allowing ready digital photodocumentation of top and bottom without even opening the box, or handling/inverting the caps -200 reportedly normals and 50 known color vision defectives could be easily tested on this modified-FM and results stored, allowing rapid turnover. The captured scores with patient ID were analyzed, at leisure, outside hospital time, saving 45-60 minutes/patient. After recording, the box was promptly handed over to the next subject for rearrangement. Times taken for test/patient were recorded. Results: Running time was reduced from 60-75 min to ~15 min/patient with no waste of invaluable lab hours. Turnover time is limited to capturing two photographs (~60 sec). The box is relatively cheap and easy to maintain. Conclusions: Our simplified FM 100-hue test allowed rapid assessment of color visions with easy data storage of both top and bottom.
  2,834 203 -
Comparison of conjunctival graft thickness after primary and recurrent pterygium surgery: Anterior segment optical coherence tomography study
Engin Bilge Ozgurhan, Necip Kara, Ercument Bozkurt, Baran Gencer, Kemal Yuksel, Ahmet Demirok
June 2014, 62(6):675-679
DOI:10.4103/0301-4738.129765  PMID:25005193
Objective: The objective of the following study is to compare the conjunctival graft thickness measured with anterior segment optical coherence tomography (OCT) after primary and recurrent pterygium excision. Design: Prospective, interventional and comparative study. Participants: A total of 20 eyes of 20 patients with primary pterygium (primary group) and 20 eyes of 20 patients with recurrent pterygium (recurrent group) were enrolled. Materials and Methods: All patients underwent pterygium excision with conjunctival autograft transplantation. Conjunctival graft thickness was measured at 1 week, 1 month and 3 months after surgery using the Visante-OCT (Carl-Zeiss Meditec, Dublin, CA, USA). Main outcome measure was the mean conjunctival thickness determined as the mean of three measurements at 1, 2 and 3 mm posterior to the scleral spur. Results: There were no statistically significant differences in age, sex, or laterality between the groups. Mean thickness of the graft in primary and recurrent groups, respectively, was 430 ± 127 μm and 461 ± 178 μm at 1 week after surgery (P = 0.587), 114 ± 19 μm and 162 ± 48 μm at 1 month after surgery (P = 0.001) and 109 ± 15 μm and 107 ± 18 μm at 3 months after surgery (P = 0.726). Conclusion: The findings revealed that conjunctival thickness after primary or recurrent pterygium excision was greatest at 1 week after surgery and continued to decrease for up to 3 months. Mean graft thickness differed significantly between the two groups only at 1 month after surgery.
  2,100 305 1
Retinal nerve fiber layer and ganglion cell complex thickness in patients with type 2 diabetes mellitus
Mehmet Demir, Ersin Oba, Hakan Sensoz, Erhan Ozdal
June 2014, 62(6):719-720
DOI:10.4103/0301-4738.136234  PMID:25005202
Aim: The aim of the following study is to evaluate the retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thickness in patients with type 2 diabetes mellitus (DM). Materials and Methods: Average, inferior, and superior values of RNFL and GCC thickness were measured in 123 patients using spectral domain optical coherence tomography. The values of participants with DM were compared to controls. Diabetic patients were collected in Groups 1, 2 and 3. Group 1 = 33 participants who had no diabetic retinopathy (DR); Group 2 = 30 participants who had mild nonproliferative DR and Group 3 = 30 participants who had moderate non-proliferative DR. The 30 healthy participants collected in Group 4. Analysis of variance test and a multiple linear regression analysis were used for statistical analysis. Results: The values of RNFL and GCC in the type 2 diabetes were thinner than controls, but this difference was not statistically significant. Conclusions: This study showed that there is a nonsignificant loss of RNFL and GCC in patients with type 2 diabetes.
  1,912 322 -
23-gauge vitrectomy with intraocular foreign body removal via the limbus: An alternative approach for select cases
Ramandeep Singh, Swapnil Bhalekar, Mangat R Dogra, Amod Gupta
June 2014, 62(6):707-710
DOI:10.4103/0301-4738.116458  PMID:24008799
Purpose: To study the outcome of removal of retained intraocular foreign bodies (RIOFBs) via limbus using 23-gauge transconjunctival sutureless vitrectomy (TSV). Materials and Methods: In this prospective, non-comparative interventional case series, fourteen eyes of 14 patients fulfilling the inclusion criteria were enrolled. They underwent 23-gauge TSV for management of posterior segment RIOFB and reviewed at 1 day, 7 days, 6 weeks, 3, 6 and 12 months. Eyes with penetrating eye injury involving cornea or limbus (corneal injury not so severe to hinder vitrectomy), cataract associated with anterior and/or posterior capsular tear requiring cataract surgery and posterior segment RIOFB with minimal posterior segment involvement were included. Main outcome measures include success in removal of RIOFB without enlarging sclerotomy, ability to preserve capsular support, improvement in visual acuity and complications, if any. Results: All eyes underwent the successful RIOFB removal through limbal port without enlarging scleral ports. None of the eyes required suturing of the sclera, cornea or conjunctiva. Anterior capsular rim could be preserved in all eyes except one. Postoperatively follow up ranged from one year in 8, 6 months in 4 and 3 months in 2 eyes. The mean logMAR visual acuity at 3, 6, and 12 months showed significant improvement. There were no intraoperative complications. Postoperative complications include microscopic hyphema and loose blood in vitreous cavity in one eye. Conclusion: The advantages of 23-gauge TSV for removal of RIOFB may be passed on to select cases. RIOFB removal through limbal route obviated the need for scleral port enlargement and preserved capsular support for early visual rehabilitation.
  1,742 232 -
Evaluation of resistive index using color Doppler imaging of orbital arteries in geriatric patients with hypertension
Ali Akal, Turgay Ulas, Tugba Goncu, Ekrem Karakas, Omer Karakas, Fatih Kurnaz, Fatima Nurefsan Boyaci, Omer Faruk Yilmaz, Abdulgafur Bata, Sema Yildiz
June 2014, 62(6):671-674
DOI:10.4103/0301-4738.136204  PMID:25005192
Background and Aim: Resistive index (RI) is an indirect measurement of blood flow resistance that can be used to evaluate vascular damage in ophthalmologic disease. The purpose of this study was to evaluate the association between RI values of orbital arteries using the color Doppler imaging (CDI) in geriatric hypertensive patients with or without retinopathy. Setting and Design: Designed as a cross-sectional study. Materials and Methods: We evaluated 60 geriatric patients with hypertension (Group 1) and 30 healthy subjects (Group 2). Further, the patients with hypertension were grouped into two: Group 1a consisted of patients with retinopathy (n = 30), and group 1b consisted of patients without retinopathy (n = 30). The mean RI values of ophthalmic artery (OA), central retinal artery (CRA), and posterior ciliary artery (PCA) were measured using CDI. Results: Compared to group 2, group 1 had significantly higher mean resistive index of PCA levels (P = 0.017), whereas there were no statistical difference in mean resistive indexes of OA and CRA (both P > 0.05). Besides, there were no statistical difference in mean resistive indexes of OA, CRA, and PCA between the group 1a and group 1b (P > 0.05 for all). Mean resistive indexes of OA, CRA, and PCA were significantly correlated with the duration of hypertension (r = 0.268, P = 0.038; r = 0.315, P = 0.014; r = 0.324, P = 0.012, respectively). Conclusions: Our study indicates that RI might be a useful marker for the ocular hemodynamic of retinal vessels, provides morphologic and vascular information in hypertension and hypertensive retinopathy.
  1,648 248 -
Evaluation of pars plana sclera fixation of posterior chamber intraocular lens
Fangju Han, Wei Liu, Xiangwei Shu, Ruili Tan, Qiang Ji, Xiangjuan Zhai
June 2014, 62(6):688-691
DOI:10.4103/0301-4738.126987  PMID:25005196
Purpose: The purpose of this study was to evaluate the clinical efficacy and safety of modified posterior chamber intraocular lens (PCIOL) implantation with transscleral fixation. Design and Setting: This is a study, which is conducted at Department of Ophthalmology, Jinan Eye Hospital, Jinan Second People's Hospital. Materials and Methods: A total of 82 patients who were scheduled for sutured PCIOL were divided randomly into modified and conventional groups. The former underwent PCIOL through pars plana fixation with knot buried and without scleral flap and the latter underwent transscleral fixation of PCIOL in the ciliary sulcus. The main outcome measures included operative time, postoperative visual acuity, and postoperative complications. Results: The mean operative time of the modified group was 39.95 ± 5.87 min, which was significantly less than that of the conventional group (45.77 ± 5.21 min; P < 0.05). No difference was found in postoperative visual acuity between the two groups. There were no significant postoperative complications, including knot exposure, endophthalmitis, and retinal detachment in either group. The optical clamping of PCIOL was prone to occur in the conventional group. Conclusion: Modified sutured PCIOL implantation is a safe, effective, and feasible technique for the correction of aphakia in eyes without adequate posterior capsular support.
  1,606 237 -
BRIEF COMMUNICATIONS
A rare case of bilateral optic nerve sheath meningioma
Somen Misra, Neeta Misra, Pratik Gogri, Rajen Mehta
June 2014, 62(6):728-730
DOI:10.4103/0301-4738.136238  PMID:25005205
A 60-year-old female presented with gradual, painless, progressive diminution of vision, and progressive proptosis of left eye since 7 years. Ophthalmological examination revealed mild proptosis and total optic atrophy in the left eye. Magnetic resonance imaging (MRI) and computed tomography (CT) brain with orbit showed bilateral optic nerve sheath meningioma (ONSM) involving the intracranial, intracanalicular, intraorbital part of the optic nerve extending up to optic chiasma and left cavernous sinus.
  1,537 200 -
Mucoepidermoid carcinoma ex pleomorphic adenoma of the lacrimal gland: A rare presentation
Lily Daniel, Shalinee Rao, Radhakrishnan Muthusamy, Deepika Yerramsetti
June 2014, 62(6):743-746
DOI:10.4103/0301-4738.136281  PMID:25005213
Carcinoma ex pleomorphic adenoma in lacrimal gland is a rare entity unlike its salivary gland counterpart. This rare tumor poses a diagnostic challenge to clinicians as pre-operative diagnosis is difficult and diagnosis is only by careful pathological assessment. We report this uncommon lesion in a 62-year-old lady, wherein the malignant component was mucoepidermoid carcinoma. The elderly patient remained clinically and radiologically free of the tumor for two years after complete excision of the tumor but computed tomography at the end of two and a half years showed a recurrent lesion in the region of the lacrimal gland. This makes long term follow up of patients with these rare lacrimal tumors imperative with a minimum period of at least five years.
  1,566 161 -
ORIGINAL ARTICLES
Association between hyperacuity defects and retinal microstructure in polypoidal choroidal vasculopathy
Moosang Kim, Seung-Young Yu, Hyung-Woo Kwak
June 2014, 62(6):702-706
DOI:10.4103/0301-4738.121132  PMID:24212209
Purpose: To improve our understanding of hyperacuity defects measured with preferential hyperacuity perimetry (PHP) by correlating PHP findings with the retinal microstructural changes visible on spectral-domain optical coherence tomography (OCT) in patients with polypoidal choroidal vasculopathy (PCV). Materials and Methods: Twenty-eight eyes of 28 patients with PCV were retrospectively reviewed. All patients underwent a complete ophthalmologic examination, including best-corrected visual acuity (logMAR) testing, PHP, and OCT. The functional 'PHP test score' and 'total volume of hyperacuity defect zone' were also analyzed. Results: Patients were classified based on the hyperacuity defect by PHP, as follows: Hyperacuity defect (n = 17 eyes) group and hyperacuity intact (n = 11 eyes) group. The mean best-corrected visual acuity in the hyperacuity intact group (0.46 ± 0.39) was better than that in the hyperacuity defect group (0.82 ± 0.37) (P = 0.014). The presence of serous retinal detachment and retinal pigment epithelial detachment did not differ significantly between groups (P = 0.120 and P = 0.689, respectively). A disrupted photoreceptor layer was more common in the hyperacuity defect group compared with the hyperacuity intact group (P = 0.0001). Among 17 eyes with a hyperacuity defect, 9 eyes showing intra-retinal pathology (intra-retinal cyst or hard exudates) and had a significantly higher PHP test score and larger total volume of the hyperacuity defect zone than 8 eyes without intra-retinal pathology (P = 0.006 and P = 0.021, respectively). Conclusion: A hyperacuity defect in PCV was associated with photoreceptor disarrangement. Furthermore, PCV lesions on the inner retina that invaded the photoreceptor layer were associated with a more severe hyperacuity defect.
  1,475 135 -
BRIEF COMMUNICATIONS
Laboratory analyses of two explanted hydrophobic acrylic intraocular lenses
Yunhai Dai, Yusen Huang, Ting Liu, Lixin Xie
June 2014, 62(6):737-739
DOI:10.4103/0301-4738.136262  PMID:25005210
Two three-piece hydrophobic acrylic intraocular lenses (IOLs) were explanted from two patients at 7 and 9 years, respectively, after implantation, because of poor fundus visualisation and/or a clinically significant decrease in visual acuity related to their opacified IOLs. In addition to light microscopy, scanning electron microscopy and energy dispersive X-ray spectroscopy, confocal laser scanning microscopy was used for the first time to observe the explanted IOLs. The clinical aspect seemed to correspond to the phenomenon of surface light scattering, while laboratory analyses showed dense glistenings in the central layer of the IOL optic, which had no change next to the surface. Further studies on these phenomena are needed.
  1,453 150 -
ORIGINAL ARTICLES
Not only pregnancy but also the number of fetuses in the uterus affects intraocular pressure
Metin Saylik, Safiye A Saylık
June 2014, 62(6):680-682
DOI:10.4103/0301-4738.120208  PMID:24178401
Aim: To investigate whether, intraocular pressure (IOP) is affected when there is a second fetus in the uterus during pregnancy. Materials and Methods: Eighty eyes of 40 twin pregnancies (TwPs), 80 eyes of 40 singleton pregnancies (SiPs) and 80 eyes of 40 non-pregnant females (NoPs) were included in the study. Statistical Analysis: Repeated measurements analysis of variance with two factors, one-way analysis of variance (ANOVA) and theTukey's multiple comparison test were used. Results: The mean IOP (MIOP) values in TwPs were 14.29 ± 1.28, 11.48 ± 1.20, and 9.81 ± 1.36 mmHg and the MIOP values in SiPs were 14.42 ± 0.95, 13.12 ± 0.75, and 10.97 ± 0.89 mmHg in subsequent trimesters. The MIOP values in NoPs were 14.77 ± 1.18, 14.92 ± 1.33, and 15.08 ± 0.89 mmHg in subsequent 3-month measurements. The results show that the MIOP values for the TwPs group were significantly lower than the SiPs in all trimesters. Conclusions: During pregnancy, the number of fetuses in the uterus is an indirectly important factor that influences the decrease in IOP. We hypothesize that the increased ocular hypotensive effect of TwPs is most likely related to the presence of higher levels of hormones, particularly estrogen, progesterone and relaxin compared with SiPs.
  1,283 191 -
OPHTHALMOLOGY PRACTICE
Bilateral monosymptomatic optic neuritis following Mycoplasma pneumoniae infection: A case report and literature review
Wei-Yu Chiang, Hsiu-Mei Huang
June 2014, 62(6):724-727
DOI:10.4103/0301-4738.136236  PMID:25005204
Herein, we report the clinical findings, treatment choice, and clinical course of a rare case of Mycoplasma pneumoniae (M. pneumoniae) infection with the sole manifestation of optic neuritis (ON). To the best of our knowledge, this is the first case presenting monosymptomatic visual loss without papillitis, neurological symptoms, and abnormal findings on brain imaging. Related articles about ON after M. pneumoniae infection were reviewed to summarize the clinical presentation, possible mechanisms, clinical survey, treatment, and prognosis of this condition. We propose that a Mycoplasma profile is necessary in children who present with ON, especially when this condition is accompanied by prodromal symptoms of the respiratory tract infection.
  1,279 192 -
ORIGINAL ARTICLES
Evaluation of macular thickness change after inferior oblique muscle recession surgery
Ece Turan-Vural, Cihan Unlu, Gurkan Erdogan, Aslan Aykut, Huseyin Bayramlar, Fatih Atmaca
June 2014, 62(6):715-718
DOI:10.4103/0301-4738.136230  PMID:25005201
Purpose: This study aimed to evaluate the changes in macular thickness following inferior oblique muscle recession surgery. Materials and Methods: Thirty-eight eyes from 21 patients undergoing ocular muscle surgery were included. Patients were grouped into three groups based on the type of surgical intervention: Group I (n = 12), inferior oblique recession surgery alone; Group II (n = 12), inferior oblique plus horizontal muscle surgery; Group III (n = 14), horizontal muscle surgery alone. Each eye was scanned using the optical coherence tomography (OCT) device preoperatively and on the first postoperative day to measure macular thickness. Results: Following surgery, a significant increase in foveal thickness occurred in Group I (P < 0.05) and Group II (P < 0.01). In addition, a statistically significant difference was observed between the groups with regard to the increase in foveal thickness (P = 0.016), with significantly lower changes in Group III. Conclusion: Our findings suggested that inferior oblique muscle recession surgery is associated with an increase in macular thickness.
  1,260 174 -
To evaluate stereoacuity in patients with acquired esotropia and to determine factors associated with favourable outcomes
Monisha E Nongpiur, Anirudh Singh, Rohit Saxena, Anudeepa Sharma, Pradeep Sharma
June 2014, 62(6):695-698
DOI:10.4103/0301-4738.136218  PMID:25005198
Aim: To evaluate stereoacuity in patients with acquired esotropia and determine the factors associated with favorable outcomes. Materials and Methods: A total of 68 subjects aged 6 years and above were included in the study. Thorough clinical evaluation including binocular status examination using the Bagolini-striated glass test, The Netherland Organization (TNO), and Randot stereo test were done. The subjects were divided into two groups 1 and 2, based on the amount of deviation. Statistical analysis of the result was performed. Result: The duration of misalignment in the group with deviation less than or equal to 8 prism diopters (PD) was 1.49 ± 0.86 years, whereas in the group with deviation more than or equal to 10 PD was 4.64 ± 2.99 years (P = 0.000). Among the subjects in group 1, 89.5% achieved fusion and 52.6% had stereoacuity on both TNO and Randot, whereas in group 2 40% achieved fusion and 3.3% stereopsis on both TNO and Randot (one case with only coarse stereopsis). A subanalysis within group 1 revealed a statistically significant difference for the duration of misalignment (P = 0.02), but a marginal difference for the amount of deviation (P = 0.3). Conclusion: A horizontal deviation up to 8 PD was compatible with stereopsis. Also, the duration of constant misalignment affects the attainment of stereopsis despite successful realignment.
  1,186 231 -
Roles of elevated intravitreal IL-1β and IL-10 levels in proliferative diabetic retinopathy
Chunjie Mao, Hua Yan
June 2014, 62(6):699-701
DOI:10.4103/0301-4738.136220  PMID:25005199
Purpose: To determine the roles of interleukin (IL)-1β and IL-10 in the vitreous of proliferative diabetic retinopathy (PDR). Materials and Methods: Vitreous samples were obtained from 26 eyes of 26 patients with PDR and from eight eyes of eight cases without PDR. The IL-1β and IL-10 concentration in the vitreous was measured by using an enzyme-linked immunosorbent assay (ELISA). Results: Levels of IL-1β and IL-10 in vitreous were higher in PDR patients compared with control group. And there was significantly negative correlation between IL-1β and IL-10 in control group (r = −0.795; P = 0.032), whereas there was no significant correlation in PDR group (r = 0.176; P = 0.391). Conclusion: Levels of IL-1β and IL-10 were upregulated in vitreous of PDR patients, and these two cytokines play roles in regulating the development and progression of PDR.
  1,207 198 -
LETTERS TO THE EDITOR
Comment: Photo essay on self-inflicted eye injury
Rupak Roy, Kumar Saurabh
June 2014, 62(6):749-750
DOI:10.4103/0301-4738.129789  PMID:25005217
  1,155 162 -
BRIEF COMMUNICATIONS
Delleman (Oculocerebrocutaneous) Syndrome: Case report
Tomás Ortiz-Basso, Rodolfo Vigo, Sebastián Iacouzzi, Jorge Prémoli
June 2014, 62(6):741-743
DOI:10.4103/0301-4738.136277  PMID:25005212
Delleman syndrome is an unusual entity, characterized by ocular cysts or microphthalmia, focal dermal anomalies and cerebral malformations. In the following article, we carry out a review of the disease and we present the case of a patient with microphthalmos and palpebral coloboma. As we could not put orbital expanders at an early stage, we performed reconstructive surgery.
  1,096 181 -
An unusual combination of Unilateral Orbital Plexiform Neurofibroma in a patient with oculocutaneous albinism
J Saravanan, A Rajendraprasad, S Priyadharshni
June 2014, 62(6):735-737
DOI:10.4103/0301-4738.136259  PMID:25005209
A 70-year-old female patient presented with proptosis of right eye for the past 15 days and defective vision in both eyes since birth. She was found to have eccentric painful proptosis of right eye along with features of oculocutaneous albinism. Eccentric proptosis was due to an orbital mass which proved to be a plexiform neurofibroma by histopathological examination. The case is presented for its rarity, as an isolated orbital plexiform neurofibroma without the systemic features of neurofibromatosis is rare and its coincidental presentation with oculocutaneous albinism is yet rare and has not been reported so far.
  1,128 149 -
EDITORIAL
Diagnostic enigmas of retinopathy: New dimensions
Sundaram Natarajan
June 2014, 62(6):669-670
DOI:10.4103/0301-4738.136203  PMID:25005191
  885 296 -
BRIEF COMMUNICATIONS
Recurrence and massive extraocular extension of choroidal malignant melanoma after vitrectomy and endoresection
Mehdi Modarres, Asgari Rezanejad, Khalil Ghasemi Falavarjani
June 2014, 62(6):731-733
DOI:10.4103/0301-4738.136247  PMID:25005207
Vitrectomy and endoresection is an alternative to enucleation for the treatment of large malignant choroidal melanoma. We report a rare case of extensive recurrence of choroidal malignant melanoma with extraocular extension 11 years after surgical endoresection without adjuvant treatment.
  1,000 145 -
Ectopic intraocular lens: An unusual complication of cataract surgery
Mehul A Shah, Shreya A Shah, Parul M Aggarwal
June 2014, 62(6):733-734
DOI:10.4103/0301-4738.136257  PMID:25005208
We wish to report an unusual complication of intraocular lens (IOL) insertion following uneventful phacoemulsification. After successful phacoemulsification surgery, a hydrophobic acrylic IOL was loaded in the injector for insertion into the capsular bag. During insertion, the IOL inadvertently extended into the corneal stromal lamella. The complication was recognized at a late stage, and the foldable acrylic lens was retrieved and reinserted correctly in the bag. The anterior chamber was made viscoelastically taut and was maintained in this state for 10 min, followed by a routine viscoelastic wash and air bubble injection. Cornea was slightly edematous with stromal haze, and the corneal thickness was 908 μm. At the 1-month follow-up visit, the patient's vision was 20/40, the stromal haze had subsided, the corneal thickness was 572 μm, and the patient was comfortable. Though it was unknown complication, following proper management patient recovered satisfactorily.
  947 171 -
Scleral buckle infection with Alcaligenes xylosoxidans
Chih-Kang Hsu, Yun-Hsiang Chang, Jiann-Torng Chen
June 2014, 62(6):739-741
DOI:10.4103/0301-4738.136266  PMID:25005211
We describe a rare case of extraocular inflammation secondary to scleral buckle infection with Alcaligenes xylosoxidans. A 60-year-old female with a history of retinal detachment repair with open-book technique of scleral buckling presented with purulent discharge and irritation in the right eye that had begun 4 weeks earlier and had been treated ineffectively at another hospital. Conjunctival erosion with exposure of the scleral buckle was noted. The scleral buckle was removed and cultured. The explanted material grew gram-negative rod later identified as A. xylosoxidans. On the basis of the susceptibility test results, the patient was treated by subconjunctival injection and fortified topical ceftazidime. After 4 weeks of treatment, the infection resolved.
  969 119 -
LETTERS TO THE EDITOR
A comparative analysis of the cost of cataract surgery abroad and in the United States
Manuel David Camejo, Mahendra K Rupani, Ronald Luke Rebenitsch
June 2014, 62(6):748-749
DOI:10.4103/0301-4738.136288  PMID:25005216
  924 152 -
BRIEF COMMUNICATIONS
A subconjunctival foreign body confused with uveal prolapse
Young Min Park, Hye-Shin Jeon, Hak-Sun Yu, Jong-Soo Lee
June 2014, 62(6):730-731
DOI:10.4103/0301-4738.136242  PMID:25005206
There are cases in which the presence of a foreign body (FB) is difficult to diagnose based on history taking or clinical examination. We report a case of subconjunctival FB confused with uveal prolapse. A 68-year-old man, who had the history of pterygium excision in his right eye, complained of irritation and congestion in that same eye. He also had the history of growing vegetables in a plastic greenhouse. It seemed to be a suspected uveal mass bulging through a focal scleral thinning site. On the basis of slit-lamp magnification, the lesion was presumed to be a hard and black keratinized mass embedded under the conjunctiva. Histopathologically, the removed mass was revealed to be a seed of the dicotyledones. Patients who show signs of prolapsed uvea or scleral thinning, possibility of a subconjunctival FB should be considered as differential diagnosis. In addition, a removed unknown FB should be examined histopathologically.
  866 153 -
LETTERS TO THE EDITOR
Surgically induced astigmatism after 3.0 mm temporal and nasal clear corneal incisions in bilateral cataract surgery
Je Hwan Yoon, Kyun-Hyung Kim, Jong Yeon Lee, Dong Heun Nam
June 2014, 62(6):753-753
DOI:10.4103/0301-4738.136308  PMID:25005221
  832 168 -
Comments on peeling and aspiration of posterior capsular epithelial pearls
Rajesh Subhash Joshi
June 2014, 62(6):750-750
DOI:10.4103/0301-4738.136299  PMID:25005218
  843 128 -
Diabetic retinopathy stabilization after renal transplantation
Yakup Aksoy, Taner Kar, Mehmet Koray Sevinc, Yusuf Emrah Eyi
June 2014, 62(6):751-752
DOI:10.4103/0301-4738.136303  PMID:25005219
  792 145 -
Course of diabetic retinopathy before and after renal transplantation
Minal Kaur, Ramesh Venkatesh, Manisha Agarwal, Rahul Mayor
June 2014, 62(6):752-752
DOI:10.4103/0301-4738.136305  PMID:25005220
  759 169 -
Comment: Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India
Tandava Krishnan, R Rajyalakshmi, Nishant Radke, Snehal Radke
June 2014, 62(6):747-748
DOI:10.4103/0301-4738.136287  PMID:25005215
  615 182 -
Completion rates of anterior and posterior continuous curvilinear capsulorrhexis in pediatric cataract surgery for surgery performed by trainee surgeons with the use of a low-cost viscoelastic
R Muralidhar, GS Siddalinga Swamy, P Vijayalakshmi
June 2014, 62(6):747-747
DOI:10.4103/0301-4738.136282  PMID:25005214
  628 119 -
Authors' Reply
Rahul Bhargava, Prachi Kumar, Shiv K Sharma, Sumat Sharma, Namrata Mehra, Anuraag Mishra
June 2014, 62(6):751-751
PMID:25136723
  373 117 -
ERRATUM
Erratum

June 2014, 62(6):679-679
PMID:25005194
  391 84 -
LETTERS TO THE EDITOR
Authors' Reply
Aditya S Kelkar, Jai A Kelkar, Shreekant B Kelkar, Devanshi Bhanushali
June 2014, 62(6):753-753
PMID:25136724
  350 114 -