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  Indian J Med Microbiol
 

Figure 1: Three years prior, a left orbital mass had been excised with pathology consistent with solitary fibrous tumor (a). Repeat magnetic resonance imaging of the left orbit showed interval recurrence of an irregular hyperintense soft tissue mass on T1-weighted images extending to the orbital apex and optic nerve (b). The primary excision showed a 22x18x15 mm encapsulated mass (c) composed of spindle cells with mildly pleiomorphic and focally overlapping nuclei (d). Repeat excision showed frankly malignant features including atypical mitoses (e, yellow arrow), nuclear pleiomorphism and focal absence of STAT6 expression on immunohistochemistry (f absence of expression black arrow, retained expression white arrow)

Figure 1: Three years prior, a left orbital mass had been excised with pathology consistent with solitary fibrous tumor (a). Repeat magnetic resonance imaging of the left orbit showed interval recurrence of an irregular hyperintense soft tissue mass on T1-weighted images extending to the orbital apex and optic nerve (b). The primary excision showed a 22x18x15 mm encapsulated mass (c) composed of spindle cells with mildly pleiomorphic and focally overlapping nuclei (d). Repeat excision showed frankly malignant features including atypical mitoses (e, yellow arrow), nuclear pleiomorphism and focal absence of STAT6 expression on immunohistochemistry (f absence of expression black arrow, retained expression white arrow)