|Year : 1972 | Volume
| Issue : 1 | Page : 23-24
An indigenous drug in the treatment of acute iridocyclitis in leprosy patients : A study in 13 patients
Dr. L. Sen Memorial Leprosy Hospital and Settlement, Asansol, West Bengal, India
S K Kundu
Dr. L. Sen Memorial Leprosy Hospital and Settlement, Asansol, West Bengal
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Kundu S K. An indigenous drug in the treatment of acute iridocyclitis in leprosy patients : A study in 13 patients. Indian J Ophthalmol 1972;20:23-4
Leprosy is fairly common in Bankura, Burdwan, Purulia and Midnapore districts of West Bengal, in Orissa, Andhra Pradesh, parts of Tamil Nadu, Maharashtra, and Madhya Pradesh. Ophthalmologists practicing in these areas often come across patients with a serious ocular complication in leprosy, which, if left untreated, leads to permanent blindness. Thanks to the modern treatment of leprosy with the Sulphone group of drugs, eye complications are now much less in number and serious ness than it was before.
MacLean and others have shown by slit-lamp examination that limbal infiltration and beading of the corneal nerves are found in fairly large number of patients even in the early stages of the disease. Cutaneous nodules on the lids, lagophthalmos, conjunctivitis, superficial and interstitial keratitis, lepromatous lesions in the sclera, granulomatous uveitis are often observed. But the commonest complication found is the involvement of the iris and Ciliary body, which can occur in either of the following forms
- Miliary leproma or iris pearls,
- Nodular leproma,
- Chronic or acute iridocyclitis,
It is this acute iridocyclitis, which comes abruptly or neglected chronic iridocyclitis which leads to blindness.
This condition occurs in case of lepromatous type of leprosy and this can occur as a symptom of "REACTION" or independently.
Treatment of such cases of iridocyclitis is done on the following lines
- Atropine sulphate 1 % drops or ointments,
(In some acute cases Mydricaine is injected subconjunctivally)
- Antibiotic-drops on ointments,
- Corticosteroid-drops or ointments topically and tablets orally,
- Vitamin C 500 mg. 1 tab. daily,
In this series 13 patients were taken up for treatment of acute cases of iridocyclitis as a complication of lepromatous leprosy in which 7 were cases with "Reaction".
In all these cases the treatment mentioned above was given, but in one group of 7 patients, in addition to the above treatment, an indigenous drug CAPYNA COMPOUND* not get this drug.
All these patients were males in the age group of 28 to 45 years. The signs and symptoms were almost the same in all these cases, except that the intensity of pain varied from patient to patient. The result of this study is tabulated below
Group A - 7 patients.
(Those who were given Capyna Comp.)
With Lepra Without Lepra
Reaction : Reaction :
Result$ - 4 Cases - 3 Cases
Very good - 4 cases - 2 cases
Good _- 1 case
Group B - 6 patients.
(Those that did not get Capyna Comp.)
With Lepra Without Lepra
Reaction : Reaction
3 Cases - 3 Cases
1 case - nil
2 cases - 2 cases
_- 1 case
$Result is judged by the disappearence of signs and symptoms as follows:
Very good : Pain subsided, conjunctival congestion and ciliary injection markedly diminished Pupil well dilated, tension normalised within 2/3 days.
Good : Above improvement noted after 5/6 days of treatment.
Poor : Pain subsided, conjunctival cogestion etc. disappeared, but cyclitic membrane formed. causing diminished vision.
The results were assessed through a blind control, in the sense that the physician who observed the cases from day to day was not aware of the group he was dealing with.
| Summary|| |
13 cases of Acute iridocyclitis as a complication of lepromatous leprosy were treated in the usual way, but 7 of them were given in addition, an indigenous drug Capyna compound. This drug seems to have a good action in such cases. The drug was well tolerated.
| References|| |
Birchn Emergencies in Medical Practice, 1956.
Dharmendra : Notes on Leprosy, 1960.
Hisakohibi : Findings in the leprous Cornea with Slit-lamp Microscopy,-Int. J. of Leprosy Vol. 24, No. 2, 1956.
Wardekar. R. V.: Hints on Diagnosis & Treatment of Leprosy, 1966.
Basu, R. N.: Eye complications in Leprosy. Leprosy in India, Oct., 1963.