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Year : 1975  |  Volume : 23  |  Issue : 4  |  Page : 36-37

Bilateral primary anophthalmos

Government Medical College, Srinagar, Kashmir, India

Correspondence Address:
Bashir Ahmad Chapu
Government Medical College, Srinagar, Kashmir
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Source of Support: None, Conflict of Interest: None

PMID: 1031158

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How to cite this article:
Chapu BA. Bilateral primary anophthalmos. Indian J Ophthalmol 1975;23:36-7

How to cite this URL:
Chapu BA. Bilateral primary anophthalmos. Indian J Ophthalmol [serial online] 1975 [cited 2021 Apr 18];23:36-7. Available from: https://www.ijo.in/text.asp?1975/23/4/36/31439

Anophthalmos is a condition wherein the eye appears clinically absent. It may be a primary anophthalmos wherein there is a failure in the development of optic cup, a secon­dary anophthalmos in which there is gross defect in the development of neural tube, or a consecutive anophthalmos in which case the degeneration takes place after the initial forma­tion of optic vesicle.[1]

  Case Report Top

A child born after lower abdominal caesearean was referred to our department with the complaint that the child did not open his eyes. The baby was born after full term and looked apparently normal, weighing 5lbs. The mother was primigravida and in good health. She did not show any abnormality. [Figure - 1]

On examination, the baby appeared healthy except­ing his eyes. There was no systemic defect. Local ocular examination revealed normal, eye lids which were, however, curved in and the palpebral aperture was small. The eyelashes were present but the lacrimal puncta could not been seen. After the lids were retrac­ted it was found that except for conjunctiva there was no ocular tissue clinically visible [Figure - 2]. The eyes on both sides gave the appearance as if the eye balls had been enucleated. There was no significant family his­tory and the mother had not taken any drugs during pregnancy.

  Discussion Top

The first case of anophthalmos was reported by Thomas Bartholin in 1657[1], his case had a bilateral anophthalmos associated with abnor­malities of nose, mouth, lips and extremeties. von Hippel[4] collected 87 cases in the literature out of which 64 cases were bilateral and 23 were unilateral.

Primary clinical anophthalmos as described by Duke-Elder' consists of a small but well formed orbit, the lids are curved-in with small orbital aperture. The orbital cavity is lined with conjunctiva. The lacrimal puncta and the eyelashes are usually present or either may be absent. Certain other associated ocular abnor­malities which have been described are ankyloblepharon,[3] epicanthus,[2] absent lacrimal gland, optic nerve and a narrow optic canal[5], an abnormal development of optic chiasma and lateral geniculate body.[6]

  Summary Top

A child with bilateral primary anophthalmos is reported.

  References Top

Duke-Elder, 1964, System of Ophthalmology, Vol. III, 416.  Back to cited text no. 1
Maclean, 1929, Amer. J. Ophthal, 12, 381.  Back to cited text no. 2
Pritikin, 1958, Brit. J. Ophthal, 45, 714.  Back to cited text no. 3
Von Hippel, V., 1899, Graefes. A. Ophthal, 47, 227.  Back to cited text no. 4
Warfel, 1961, Amer. J. Ophthal, 51, 698.   Back to cited text no. 5
Woolard, 1926, Brit. J. Ophthal. 10, 131.  Back to cited text no. 6


  [Figure - 1], [Figure - 2]


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