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Year : 1977  |  Volume : 25  |  Issue : 2  |  Page : 3-4

Serum immunoglobulins in phlyctenulosis

Banaras Hindu University, Varanasi, India

Correspondence Address:
R N Tyagi
Department of Ophthalmology, M.M.G. 4, Chhittupur Doctors' Enclave, B.H.U., Varanasi-221005 (UP).
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Source of Support: None, Conflict of Interest: None

PMID: 615148

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How to cite this article:
Tyagi R N, Thakur V, Gupta RM. Serum immunoglobulins in phlyctenulosis. Indian J Ophthalmol 1977;25:3-4

How to cite this URL:
Tyagi R N, Thakur V, Gupta RM. Serum immunoglobulins in phlyctenulosis. Indian J Ophthalmol [serial online] 1977 [cited 2022 Oct 4];25:3-4. Available from: https://www.ijo.in/text.asp?1977/25/2/3/31247

Table 2

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Table 2

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Table 1

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Table 1

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Several recent reports are available in literature regarding serum immunoglobulin in eye diseases like uveitis, Eale's, trachoma and keratitis.[1] However, not a single report could be found related to Phlyctenulosis. Serum immunoglobulins (G, A & M) were estimated to find out whether there was a change in the levels in phlyctenular cases.

  Materials and Methods Top

Twenty-nine healthy individuals (Group A) and twenty-nine cases of phlyctenulosis (Group B) were subjected to this study. Cases in both groups belonged to same age group.

Besides other routine investigations, the serum im­munoglobulins were estimated by single radial diffusion method.

  Results Top

[Table - 1] shows the levels of serum im­munologlobulin G, A and M in individual cases of phlyctenulosis.

Statistically there is highly significant rise in serum IgG level (P=< 0.001) and significant rise in IgM level (P= <0.05) in cases of phlyc­tenulosis [Table - 2]

  Discussion Top

The differential analysis of various serum immunogobulins in normal subjects in our study reveals that mean values of different fractions more or less approximated with those reported by Hobbs and Hepner[3], Sehgal and Aikat[4] and Gupta et al.[2]

In phlyctenulosis cases the serum immuno­globulin G and M are found to be at significantly higher levels (P=

  Summary Top

Estimation of serum immunoglobulin G, A and M was carried out in 29 healthy indivi­duals and 29 cases of phlyctenulosis. The serum IgG and IgM were sigificantly raised in cases of phlyctenulosis as compared to normal subjects.

  Acknowledgement Top

We thank Mr. R.J. Verma for his kind help in this study.

  References Top

Fahey, J.L.. 1968. W.H.O. Immunology Work­shop notes. All India Institute of Medical sciences, New Delhi, India.  Back to cited text no. 1
Gupta. R.M.. Gupta. V,M. and Marwah. S.M.. 1975. Ind. Jour. Med. Res., 63, 1055.  Back to cited text no. 2
Hobbs. J.R. and Hepner. G.M.. 1968. Lancet , 217.  Back to cited text no. 3
Sehgal, S. and Aikat, B.K., 1970, Ind. Jour. Med. Res., 58, 289.  Back to cited text no. 4


  [Table - 1], [Table - 2]


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