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   Table of Contents      
ARTICLE
Year : 1980  |  Volume : 28  |  Issue : 2  |  Page : 63-66

Palmar dermatoglyphics in corneal dystrophy


1 Department of Genetics, Osmania University, Hyderabad, India
2 Institute of Ophthalmology, Sarojini Devi Eye Hospital, Hyderabad, India

Correspondence Address:
T Padma
Deptt. of Genetics, Osmania University, Hyderabad
India
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Source of Support: None, Conflict of Interest: None


PMID: 6971255

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How to cite this article:
Padma T, Murty J S, Reddy P R. Palmar dermatoglyphics in corneal dystrophy. Indian J Ophthalmol 1980;28:63-6

How to cite this URL:
Padma T, Murty J S, Reddy P R. Palmar dermatoglyphics in corneal dystrophy. Indian J Ophthalmol [serial online] 1980 [cited 2020 Oct 26];28:63-6. Available from: https://www.ijo.in/text.asp?1980/28/2/63/28224

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Table 1

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The study of dermatoglyphics acquired considerable importance as a parameter in assessing their association with diseases and as one of the diagnostic features in certain chromosomal anomalies, syndromes and congenital malformations.[1],[2] Though informa­tion is available on dermatoglyphic profiles in some common diseases like leukemia, diabetes, congenital malformations, heart diseases etc.,[2] their usefulness in diagnosing these conditions is not yet confirmed. Attempts were also made to find association of dermato­glyphics with some eye diseases like retinoblas­toma,[3],[4] senile cataract,[5] glaucoma myopia[6] and strabismus[7].

The present report relates to the variations in dermal configurations in cases with corneal dystrophy.


  Material and methods Top


Palm prints of 34 cases of corneal dystro­phies were studied for the variations in their dermal configurations. These cases were diagnosed at the corneal clinic of Sarojini Devi Eye Hospital, Hyderabad and include different types of dystrophies. Ten of the cases studied showed positive family history.

The dermatoglyphic analysis was made following Cummins and Midlo[8] The results were compared for their differences with a random population control and for differences between familial and isolated cases.

The caste wise and ethnic distribution in the patients with the condition was more or less similar to that in the local population.


  Results and discussion Top


Corneal dystrophy cases differed signifi­cantly from the controls in the incidence of finger print patterns [Table - 1]. This difference was mainly due to an increase in whorls (44.9%) and decrease in ulnar loops (51.8%) in the disease group. Such an increase in whorl pattern has already been reported in conditions like glaucoma and myopia,[6] congenital rubella,[9] psoriasis,[1°] in aortic stenosis,[11] in rheumatic fever and heart diseases,[12],[13] Contrary to this ulnar loops and arches are known to be increased in certain chromosomal anomalies.[2]

Between familial and isolated cases no remarkable variations in the finger patterns were observed.

The incidence of patterns were significantly high on thenar, a-b, b-c and c-d regions of the palms while it was low on the hypothenar region in corneal dystrophy when compared to controls [Table - 2]. Familial cases showed an increase in the frequency of patterns on c-d region and decrease on b-c and thenar regions when compared to isolated cases. There are very few reports on the interdigital patterns and among the eye afflictions, glaucoma[6] and strabismus[7] showed similar trend with an increase in the incidence of loops.

The mean total ridge counts and interdigi­tal counts in corneal dystrophy did not differ significantly while atd angles showed higher values as compared to controls [Table - 3]. The significant increase in the mean pattern intensity index in corneal dystrophy is a consequence of higher incidence of the whorl patterns.

Except for B-line all the main line termina­tions in dystrophic cases significantly differed from the controls [Table - 4]. The differences are apparently the result of low frequency of D-line terminating at 9th and 11th positions, low frequency of C-lines terminating at 7th and 9th positions and high frequency at 5th position and high frequency of A-lines termina­ting at 4th and low frequency at 5th position on palms of the patients when compared to controls. Between familial and isolated cases C and A lines showed significant differences x3-36.22 with P<0.01 and 8.10 with P<0,05. Studies on the main line polymorphisms are confined mostly to populations and very few attempts have been made to examine their role and association with common diseases. The significant associations of main line termina­tions as found with corneal dystrophy under­lines their possible association with other diseases.

Though it is difficult to provide explanation per se for the increase in whorls and incidence of palmar patterns in corneal dystrophy patients, certain pleiotropic mechanisms are likely to be involved in the association.

Further studies on these aspects in different dystrophic conditions and other eye diseases is worth pursuing.


  Summary Top


The study of palm prints of 34 cases with corneal dystrophy showed a significant increase in whorl and decrease in ulnar loop patterns as compared to controls. The patterns occurred with high frequencies on thenar, a-b, b-c and c-d regions and with low frequency on hypo­thenar region. No significant variations were observed in the mean finger and interdigital ridge counts and atd angles. All the main line terminations except for B showed signi­ficant differences as compared to controls. Between familial and isolated cases C and A lines revealed significant variations.


  Acknowledgements Top


The authors are thankful to Professor O.S. Reddi, former Head, Department of Genetics, Osmania University and Dr. P. Siva Reddi, Director and Dr. C.S. Sharma, Superintendent, Sarojini Devi Eye Hospital and Institute of Ophthalmology, Hyderabad, for providing the required facilities during the course of the study.

 
  References Top

1.
Holt, S.B , 1968, The genetics of dermal ridges. Charles Thomas Publishers, Illinois, U.S.A.  Back to cited text no. 1
    
2.
Schauman, B., and Alter, M., 1976, Dermato­glyphics in medical disorders. Springer-Verlag. New York.  Back to cited text no. 2
    
3.
Francois, J., Matton-Van, M.T., Debie, Leu Ven, S., 1969 J. Genet. Human. 17: 367.  Back to cited text no. 3
    
4.
Vidal, O.R., Darnel, A. and Furies, J.C., 1969, J. Genet Hun., 17: 19.  Back to cited text no. 4
    
5.
Murty, J.S , 1973, East. Arch. Ophthalmol., 1:17,  Back to cited text no. 5
    
6.
Jain, C., 1974, Dermatoglyphics in some of the eye diseases. M.Sc. dissertation, Osmania University, India.  Back to cited text no. 6
    
7.
Kumudini, M., 1975, A study of genetic factors in strabismus and corneal dystrophy. M Sc. disserta­tion, Osmania University, India.  Back to cited text no. 7
    
8.
Cummins, H., and Midlo, C., 1943, Finger prints palms and soles, The Blackiston Company, Philadelphia.  Back to cited text no. 8
    
9.
Chandra. R K., 1969, Hum. Hered , 19:540.  Back to cited text no. 9
    
10.
Gibs. R.C. and Warburton, D., 1968, J. Invest. Dermatol. 51: 259.  Back to cited text no. 10
    
11.
Cascos, A.S., 1964, Brit. Heart. J., 26: 524.  Back to cited text no. 11
    
12.
Puri, R.K., Indira Narayan, Balakrishnan, S., 1971. Proc. Xth National Conference of Indian Academy of Pediatrics.  Back to cited text no. 12
    
13.
Annapurna, V., Ahuja, Y.R., Reddi, G.D. Shankar Rao, V. and Niranjan Rao, P., 1978, Hum, Hered.. 28, 72.  Back to cited text no. 13
    



 
 
    Tables

  [Table - 1], [Table - 2], [Table - 3], [Table - 4]



 

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