Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 3181
  • Home
  • Print this page
  • Email this page

   Table of Contents      
ARTICLES
Year : 1981  |  Volume : 29  |  Issue : 3  |  Page : 303-305

A study on transaminase level in aqueous humour


1 Department of Ophthalmology, Calcutta National Medical College, Calcutta, India
2 Department of Biochemistry, Calcutta National Medical College, Calcutta, India

Correspondence Address:
K K Sengupta
Department of Ophthalmology, Calcutta National Medical College, Calcutta
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 7346449

Rights and PermissionsRights and Permissions

How to cite this article:
Sengupta K K, Das A K, Bose R, Chatterjee A, Mukherji R. A study on transaminase level in aqueous humour. Indian J Ophthalmol 1981;29:303-5

How to cite this URL:
Sengupta K K, Das A K, Bose R, Chatterjee A, Mukherji R. A study on transaminase level in aqueous humour. Indian J Ophthalmol [serial online] 1981 [cited 2020 Dec 1];29:303-5. Available from: https://www.ijo.in/text.asp?1981/29/3/303/30907

Table 3

Click here to view
Table 3

Click here to view
Table 2

Click here to view
Table 2

Click here to view
Table 1

Click here to view
Table 1

Click here to view
The enzymes, glutamic-oxalo-acetic transa­minase (G.O.T.) and glutamic pyruvic transa­minase (G.P.T.) are widely distributed in the cells of human body and destruction of any cell leads to leakage of these enzymes in the blood stream.

The aim of the present study is (i) to find out the normal level of G.O.T. and G.P.T. in aqueous humour and also (ii) to observe whether in conditions where G.O.T. and G.P.T. level is increased in blood, there is corresponding increase of these enzymes in aqueous humour.


  Materials and methods Top


For the purpose of this study, the G.O.T. and G.P.T. content of blood and aqueous humour of 24 individuals were estimated. All these individuals were patients of the Eye Department of the Calcutta National Medical College, Hospital and underwent surgery for cataract. The subjects were divided into Groups A and B Group A comprising of 12 healthy individuals, in whom no disease other than cataract could be detected, con­stituted the normal control series. GroupB comprised of 12 individuals who were known sufferers of diseases like cirrhosis liver and connective tissue disorders. The samples of blood and aqueous from patients of both the series were collected during cataract surgery. The transaminase content in blood and aqueous was estimated by calorimetric techni­que of Mohum and Cook.[1]


  Observations and discussions Top


The G.O.T. and G.P.T. levels in aqueous and blood of individuals belonging to Group A and Group B is shown in [Table - 1][Table - 2] respectively.

It has been observed in the present study that the normal G.O.T. and G.P.T. level in aqueous is 24.3 + 0.7 1.U. /ml and 23.2 + 0.6 I U/ml. respectively [Table - 3]

[Table - 3] further reveal that transaminase level of aqueous is more or less constant in individuals of both Groups A and B although the blood level of these enzymes is much higher in the Group B individuals. Thus, there has been no appreciable rise in the G.O.T. level of aqueous humour even when these enzymes in blood are as higher as double its normal level (64 to 74 I.U./ml.).


  Summary Top


The G.O.T. and G.P.T. levels of aqueous and blood were estimated in two Groups of individuals -one constituted the normal con­trol series who had no systemic disease and the other group of patients who were known sufferers of diseases which cause high trans­aminase content in blood. When the results of both the groups were compared, it was observed that the transaminase level in aqueous remained within normal limits even in cases where there were high serum trans­aminase.


  Acknowledgements Top


We are thankful to Dr. H.N. Ghosh, Principal-Superintendent, Calcutta National Medical College & Hospitals for kindly allow­ing us to carry out this work and to publish it.

 
  References Top

1.
Mohum, A.F. and Cook, I.J.Y., 1957, J. Clin. Path. 10 : 394.  Back to cited text no. 1
    



 
 
    Tables

  [Table - 1], [Table - 2], [Table - 3]



 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
Materials and me...
Observations and...
Summary
Acknowledgements
References
Article Tables

 Article Access Statistics
    Viewed1552    
    Printed48    
    Emailed0    
    PDF Downloaded1    
    Comments [Add]    

Recommend this journal