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Year : 1982  |  Volume : 30  |  Issue : 3  |  Page : 161-162

Tuberous xanthoma of upper eye lids

Department of Ophthalmology, S.M.S. Medical College, Jaipur, India

Correspondence Address:
Yogesh Shukla
Deptt. of Ophthalmology, S.M.S. Medical College, Jaipur
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Source of Support: None, Conflict of Interest: None

PMID: 7174063

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How to cite this article:
Shukla Y, Ratnawat P S. Tuberous xanthoma of upper eye lids. Indian J Ophthalmol 1982;30:161-2

How to cite this URL:
Shukla Y, Ratnawat P S. Tuberous xanthoma of upper eye lids. Indian J Ophthalmol [serial online] 1982 [cited 2021 May 8];30:161-2. Available from: https://www.ijo.in/text.asp?1982/30/3/161/28199

Xanthomas are aggregation of fat laden macrophages in the cutis and subcutaneous tissue. The usual lesion is xanthelasma which occurs as yellowish, slightly raised patches in the lids near the inner canthus, but rarely a nodular lesion of considerable size may occur in the lids. Such tuberous xanthomas may be comparatively acute and sometimes a single nodule may appear as a small firm tumour.

  Case report Top

50 years old female was seen in nearby eye camp with the complaint of bilateral swell­ing of upper eye lids, since 3 years. The swelling was gradually progressive, painless and hot associated with any other symptoms. On examination the swelling was nodular, extending throughout the lids, firm in consis­tency, non tender and the skin was adherent to the swelling. Her routine investigations of T.L.C., D.L.C., E.S.R. and urine were normal. Her serum cholesterol and blood sugar were also within normal limits. Plin X-ray showed no bony involvement. A biopsy was taken and the patient advised to report again at the Medical College Hospital. The biopsy report showed large pale staining fat laden histiocytes with granular or foamy cytoplasm and small, dark staining fibroblasts in the subcutaneous tissue. The infiltration was deep invading the orbicularis muscle also [Figure - 1].

  Discussion Top

Xanthomas are more common in female patients with normal serum cholesterol levels at around the fifth decade[2]. They may also occur in the lids in patients with primary hyper cholesterolemia or as secondary xantho­matosis. They develop slowly, may be itchy or tender and occasionally small nodules may involute and disappear. Effective treatment is total excision.

  Summary Top

A case of tuberous xanthoma of both upper eye lids in female patient with normal serum cholesterol level is presented. The tumour is an uncommon form of xanthoma, the usual type being a xanthelasma.[4]

  References Top

Duke Elder, S., 1972, System of Ophthalmology ocular adnexa. Vol. XIII. Henry Kimpton, London.  Back to cited text no. 1
Hogan, M.J. and Zimmerman, L.E., 1962, Oph­thalmic pathology (second edition) Published by W.B. Saunders Co. London & Philadelphia.  Back to cited text no. 2
O'brien, C.S. and Braley, A.E., 1936, J. Amer. Med. Assoc. 107: 933.  Back to cited text no. 3
Roe, D.A., 1968, Arch. Dermatol. 97:436.  Back to cited text no. 4


  [Figure - 1]


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