|Year : 1983 | Volume
| Issue : 5 | Page : 552-553
Role of fluorescein angiography in choroiditis
SP Garg, HK Tewari, PK Khosla
Dr. Rajendra Prasad Centre for Ophthalmic Sciences A.I.I.M.S., New Delhi, India
S P Garg
Dr. Rajendra Prasad Centre for Ophthalmic Sciences A.I.I.M.S., New Delhi 110 029
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Garg S P, Tewari H K, Khosla P K. Role of fluorescein angiography in choroiditis. Indian J Ophthalmol 1983;31:552-3
Choroid and retina are closely adherent structures and hence inflammation of retina causes some inflammation of choroid & vice versa.
In choroiditis there is associated inflammation of retina and the barrier effect of pigment epithelium is lost. Fluorescein angiography therefore demonstrates the leak. This property of fluorescein angiography was used in all clinical diagnosed cases of choroiditis to study the (a) activity of the lesion (b) to know the extent of lesion (c) to differentiate cases of macular oedema due to choroiditis or peripheral uveitis from cases of typical central serous retinopathy.
| Material and Methods|| |
Fluorescein angiography was done in 50 cases of choroiditis who presented in the Uvea Clinic of Dr. Rajendra Prasad Centre for Ophthalmic Sciences. Clinical examination with slit lamp; Ophthalmoscopy (direct & Indirect) & Goldman's Three Mirror. Examination was performed in all the cases. Depending on the area affected these cases were labelled as central, disseminated or diffuse choroiditis. Seeing the cells in anterior chamber, cells in the vitreous oedema of retina and pigmentation on the retina were labelled as healed or active. Non resolving cases of clinically diagnosed central serous retinopathy were also studied for central choroiditis.
Depending on the activity of the lesions these cases were put on different treatment. Cases of non-resolving central serious retinopathy were put on anti-tubercular treatment. Cases were followed up and Fluorescein Angiography done on every fornight for any activity of the lesion.
| Observations and Discussion|| |
Out of 50 cases diagnosed as choroiditis, on clinical parameters, 9 were of macular choroiditis, 28 of disseminated and 13 of diffuse choroiditis. Clinically 28% showed activity i.e. 4 of macular choroiditis 2 of disseminated and 4 of diffuse choroiditis. [Table - 1].
Out of 9 cases of macular choroiditis 2 cases showed active patches of choroiditis outside the macular area on fluorescein angiography and therefore labelled as cases of disseminated choroiditis instead of macular choroiditis. Out of 5 cases diagnosed clinically as healed, 2 cases showed leakage on late phase of fluorescein angiography & were transferred in the category of active macular choroiditis.
Clinically only 8 cases were diagnosed as active disseminated choroiditis, an additional 5 cases were picked up on the basis of a leak by fluorescein angiography. In another 3 cases, fluorescein angiography showed presence of a leak in the normal looking retina between the different patches of disseminated choroiditis. These 3 cases hence were labelled as diffuse choroiditis.
Out of 13 cases of clinically diagnosed diffuse choroiditis, 9 were healed and 4 were active. Here also fluorescein angiography picked up 2 active cases from clinically diagnosed healed cases. Active cases were put on treatment and followed up by fluorescein angiography. Treatment was stopped only when no leakage were detected.
| Summary and Conclusions|| |
Fifty cases of Choroiditis from Uvea Clinic of Dr. Rajendra Prasad Centre for Ophthalmic Sciences were studied. Clinical cases were classified into macular, dissaminated or diffuse choroiditis. Fluorescein angiography was done in each case. Twenty six per cent of the cases were diagnosed active clinically while fluorescein angiography showed activity in changed 42% of cases. Some of the cases diagnosed as macular choroiditis were found to be of disseminated choroiditis and that of disseminated proved to be of diffuse choroiditis. It was concluded that fluorescein angiography is a better parameter for their control of the treatment and also to judge activity. It also helps in proper diagnosis of patients, so indirectly might throw some light on aetiology.
[Table - 1]