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   Table of Contents      
Year : 1984  |  Volume : 32  |  Issue : 2  |  Page : 97-98

Conjunctival dysplasia

1 Department of Ophthalmology, Mahatma Gandhi Institute of Medical Sciences, Sevagram- Wardha, India
2 Department of Pathology, Mahatma Gandhi Institute of Medical Sciences, Sevagram- Wardha, India

Correspondence Address:
S S Sane
Deparment of Ophthalmology & Pathology, Mahatma Gandhi Institute of Medical Sciences, Sevagram-Wardha
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Source of Support: None, Conflict of Interest: None

PMID: 6526474

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How to cite this article:
Sane S S, Khan N, Ingole N S. Conjunctival dysplasia. Indian J Ophthalmol 1984;32:97-8

How to cite this URL:
Sane S S, Khan N, Ingole N S. Conjunctival dysplasia. Indian J Ophthalmol [serial online] 1984 [cited 2021 Jan 21];32:97-8. Available from: https://www.ijo.in/text.asp?1984/32/2/97/27380

Hyperplasia of conjunctival epithelium with dysplastic changes are rare. Very rarely conjunctiva is so much hypertrophied that it resemble malignant growth.

  Case report Top

A 24 years Hindu male was admitted with complaints of progressive swelling in left eye since 3 months and inability to open left eye. To start with swelling was in the form of a .nodule in the bulbar conjunctiva near lateral canthus, which gradually ballooned out to surround whole of cornea. No history sugges­tive of Tuberculosis, Leprosy, Trauma or similar swelling in the past.

Patient of average built, no anaemia, no jaundice. No lymphadenopathy. The growth was occupying whole of the anterior segment of eye and ballooning out about 1 cm out side the palpebral aperture surface was smooth, firm and no tender. There was no bleeding points from surface and it was reddish pink in colour. There was no involvement of lids, but movements of lids resisted because of growth. There was marked chemosis of con­junctiva and restriction of ocular movements.

Rest of anterior segment were normal [Figure - 1]. Acuity of vision of RE 6/6 but in L/E it could not be recorded. Investigations including X-ray orbit (P.A. lateral view) and peripheral blood smear showed no abnormality.

A biopsy specimen of the growth was taken which showed hyperplasia of conjunctival tissue with dysplastic changes and chronic inflammatory reaction [Figure - 2].

The patient was kept on systemic and local corticosteroids. The swelling subsided and the vision was 6/6 when the patient was dis­charged [Figure - 3].

  Discussion Top

This type of hyperplasia can be due to irritation, ulceration, injury, (Foreign body, corn, stalk, vegetable matter chalazion, burst­ing in eye, artificial eye). It may be sessile or polypoid. It may be very much vascularised causing bloody tear and become ulcerated to look like malignant growth.

In this condition the cells are thick and hypercellular. Abnormal cells are abnor­mally present in cell arrangement. Similar to but less numerous than carcinoma in situ. The most important differences are the pathological changes do not extend through whole thickness of epithelium. Epithelial dys­phasia exhibits a spectrum of cellular abnor­malities ranging from mild to severe. Mild dysplasia is not a severe dysplasia and is pro­bably reversible severe dysplasia begins to approximate, for carcinoma in situ and will sometime progress to carcinoma if left untreated.

  Summary Top

Avery rare case of conjunctival dysplasia resembling malignant growth clinically has been described, which responded well to treatment. A growth resembling malignancy, should always be examined his­topathologically before drastic operations are undertaken.[3]

  References Top

Duke Elder, 1965, System of Ophthalmology: Henry Klimpton Publications, London: Inflammatory Hyperplasias, 8,11: 1180.  Back to cited text no. 1
Greer C.H., 1972, Ocular Pathology: Blackwell Scientific Publications, London, "Conjunctival epithe­lial dysplasia., II: 99.  Back to cited text no. 2
Zimmerman, 1962, Ophthalmic Pathology: W.B. Saunders Company. London. Inflammatory of con­junctiva. II: 275.  Back to cited text no. 3


  [Figure - 1], [Figure - 2], [Figure - 3]


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