| ORIGINAL ARTICLE |
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| Year : 2000 | Volume
: 48
| Issue : 1 | Page : 15-9 |
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Eye tracking disturbances in Schizophrenia
P Sharma, BS Aslam, S Saxena
Centre for Ophthalmic Sciences, All Institute of Medical Sciences, Ansari Nagar, New Delhi-110 029, India
Correspondence Address:
P Sharma
Centre for Ophthalmic Sciences, All Institute of Medical Sciences, Ansari Nagar, New Delhi-110 029
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 11271928 
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Purpose: To study the frequency of different types of eye tracking disturbances in schizophrenia.
Materials and Methods: Smooth pursuit eye movements were studied by electro-oculography (EOG) in 22 schizophrenic patients (ICD-10 criteria) and 15 age and sex-matched controls. The studied parameters included average pursuit gain, number of saccades, the frequency of different types of saccades (catch-up, back-up, anticipatory saccades), and disturbances during fixation. The results were analysed statistically.
Results: The average pursuit gain was significantly affected in patients for target velocity of 30°/sec (p=0.007). The catch-up and back-up saccades were more common in cases than controls but the difference was not significant (p=0.39 and 0.36 respectively). The anticipatory saccades were significantly more frequent in cases than controls (p<0.0001) for both 15°/sec and 30°/sec target velocities. This was also correlated with the duration of illness.
Conclusion: Anticipatory saccades are significantly more frequent during eye tracking in schizophrenia and appear to be an objective marker for the disease.
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