ORIGINAL ARTICLE |
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Year : 2000 | Volume
: 48
| Issue : 3 | Page : 217-21 |
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Nocardia Asteroides Keratitis: Report of seven patients and literature review
SK Rao, HN Madhavan, G Sitalakshmi, P Padmanabhan
Medical Research Foundation, 18 College Road, Chennai-600 006, India
Correspondence Address:
S K Rao Medical Research Foundation, 18 College Road, Chennai-600 006 India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 11217254 
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Purpose: To describe clinical features and treatment outcomes in patients with advanced Nocardia asteroides keratitis.
Methods: Retrospective review of case records of 7 patients with culture-proven Nocardia keratitis.
Results: Corneal infection occurred after corneal trauma in two patients, cataract surgery in three patients, penetrating keratoplasty in one patient and was associated with a silicone buckle element infection in one patient. Mean duration of infection at presentation was 33.4 days (7-75 days), and five patients had received prior treatment with corticosteroids. Six of seven patients had deep corneal suppuration at the time of: presentation, clinically suggestive of mycotic keratitis. In two patients who had received prolonged corticosteroid therapy (≥ 45 days), the eyes could not be salvaged. Complete resolution of infection was achieved in all 4 eyes treated with topical fortified cefazolin eye drops (50mg / ml).
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