Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 2175
  • Home
  • Print this page
  • Email this page
Year : 2004  |  Volume : 52  |  Issue : 2  |  Page : 127-31

Sterile Endophthalmitis in Vitrectomised Eyes due to Suspected Heat Resistant Endotoxins in the Infusion Fluid

Retina Associates Eye Institute, New Delhi, India

Correspondence Address:
B Patnaik
Retina Associates Eye Institute, New Delhi
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 15283217

Rights and PermissionsRights and Permissions

Purpose: To report on to the possibility of development of severe postoperative sterile endophthalmitis due to heat-resistant bacterial endotoxins in commercially available infusion fluids Methods: A case study of 4 eyes that had previously undergone vitreoretinal surgery, which developed clinical endophthalmitis within 18 hours of surgery and two eyes that had vitreous surgery with intraocular gas and did not develop clinical endophthalmitis following intraocular surgery on three consecutive operative days Results: The vitreous samples were sterile, both for bacteria and fungi. The only common supply in all cases was a new batch of Ringer's lactate infusion fluid. Though the Ringer's lactate solutions in the same batch were also sterile, the infusion fluids contained abnormally high levels of bacterial endotoxins detected by gel clot method. Conclusion: Commercially available infusion fluid may be sterile, yet contain endotoxins from killed bacteria. This could cause postoperative sterile endophthalmitis.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded229    
    Comments [Add]    
    Cited by others 3    

Recommend this journal