ORIGINAL ARTICLE |
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Year : 2006 | Volume
: 54
| Issue : 1 | Page : 17-22 |
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Role of frequency doubling technology perimetry in screening of diabetic retinopathy.
Rajul Parikh1, Milind Naik1, Annie Mathai1, Thomas Kuriakose1, JayaPrakash Muliyil2, Ravi Thomas1
1 Schell Eye Hospital, Christian Medical College, Vellore, India 2 Department of Community Health, Christian Medical College, Vellore, India
Correspondence Address:
Ravi Thomas L. V. Prasad Eye Institute, L.V. Prasad Marg, Banjara Hills, Hyderabad 500034 India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0301-4738.21609
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Purpose: To study the ability of frequency-doubling technology perimetry (FDT) to detect sight-threatening diabetic retinopathy.
Method: Fifty-eight eyes of fifty-eight patients with established diagnosis of diabetes mellitus with diabetic retinopathy, fifty-five eyes of fifty-five diabetic patients without retinopathy, and forty-one eyes of forty-one normals underwent FDT and dilated stereo-biomicroscopic fundus examination. The sensitivity and specificity of FDT in identification of "sight-threatening retinopathy" (severe and very severe nonproliferative diabetic retinopathy and proliferative diabetic retinopathy) and clinically significant macular edema (CSME) were determined.
Results: For the detection of sight-threatening retinopathy, two abnormal adjacent points depressed to any level on the 20-1 screening program had a sensitivity of 90.5% and specificity of 97.6%. At (assuming a) 10% prevalence of sight-threatening retinopathy in a diabetic clinic, two abnormal adjacent points anywhere in the field depressed to any level has a positive predictive value (PPV) of 48% with a negative predictive value of 98.8%. Sensitivity and specificity for the detection of CSME was poor.
Conclusions: The 20-1 screening program of the FDT is useful in the detection of sight-threatening diabetic retinopathy (PPV 48%). A normal 20-1 test rules out sight-threatening retinopathy. FDT was not useful in the detection of CSME. |
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