| ORIGINAL ARTICLE |
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| Year : 2007 | Volume
: 55
| Issue : 5 | Page : 331-336 |
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Retinopathy of prematurity in Asian Indian babies weighing greater than 1250 grams at birth: Ten year data from a tertiary care center in a developing country
Anand Vinekar1, Mangat R Dogra1, Tiakumzuk Sangtam1, Anil Narang2, Amod Gupta1
1 Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Correspondence Address:
Mangat R Dogra
Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0301-4738.33817
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Background: Retinopathy of prematurity (ROP) is an important cause of childhood blindness in developing countries.
Aim: To report the spectrum of ROP and associated risk factors in babies weighing > 1250 g at birth in a developing country.
Setting and Design: Institutional, retrospective, non-randomized, observational clinical case series.
Materials and Methods : Retrospective analysis (10 years) of 275 eyes (138 babies) with ROP.
Statistical Analysis: Qualitative data with the Chi-square test. Quantitative data using the unpaired t test or the ANOVA and further tested using multivariate logistic regression.
Results: The mean birth weight was 1533.9 g (range 1251 to 2750 g) and the mean period of gestation was 30.9 weeks (range 26 to 35). One hundred and twenty-four of 275 eyes (45.1%) had threshold or worse ROP. Risk factors for threshold or worse disease were, 'outborn babies' ( P < 0.001), respiratory distress syndrome ( P = 0.007) and exchange transfusion ( P = 0.003). The sensitivity of the American and British screening guidelines to pick up threshold or worse ROP in our study group was 82.4% and 77.4% respectively.
Conclusions : Severe ROP is often encountered in babies weighing greater than 1250 g at birth in developing countries. Western screening guidelines may require modifications before application in developing countries. |
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