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Year : 2008  |  Volume : 56  |  Issue : 5  |  Page : 429-430

Bovine pericardium in treating large corneal perforation secondary to alkali injury: A case report

Department of Ophthalmology, School of Medical Sciences, University Sains Malaysia, Malaysia

Correspondence Address:
Rajesh K Khanna
17.6.15, Palladium Condominium, Jalan Gurney-2, 54000 Kuala Lumpur
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0301-4738.42426

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To describe use of a locally processed bovine pericardium (BP) to cover a large central corneal perforation following alkali injury and discuss postoperative outcome. A 27-year-old Malay male patient presented two weeks after alkali splashed in his left eye while working. A clinical diagnosis of left central corneal ulcer with limbal ischemia following alkali injury with secondary infection was made. After failed medical therapy, we performed a Gunderson conjunctival flap under local anesthesia that retracted after one week and resulted in a large central corneal perforation with surrounding stromal thinning. The perforation was covered with a locally processed BP xenograft (Lyolemb) supplied by the National Tissue Bank, University Sains Malaysia. Nine months follow-up showed a well-taken graft without any exposure/dehiscence and minimal inflammation. Amniotic membrane transplantation when used as a patch graft needs an urgent tectonic graft to promote corneal stability in patients with severe corneal thinning. The use of processed BP can be a viable option in treating such cases.

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