BRIEF COMMUNICATION |
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Year : 2010 | Volume
: 58
| Issue : 1 | Page : 76-78 |
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Intravitreal anti-vascular endothelial growth factor agents as an adjunct in the management of Coats' disease in children
Shalini Kaul, Mahesh Uparkar, Kruti Mody, Jaydeep Walinjkar, Mihir Kothari, S Natarajan
Department of Pediatric Ophthalmology and Strabismology, Aditya Jyot Eye Hospital Pvt Ltd, Mumbai, India
Correspondence Address:
Shalini Kaul Department of Pediatric Ophthalmology and Strabismology, Aditya Jyot Eye Hospital Pvt. Ltd, Plot no 153, Road no 9. Major Parmeswaran Road, Wadala, Mumbai - 31 India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0301-4738.58480
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We describe the role of intravitreal anti-vascular endothelial growth factor (VEGF) agents in Coats' disease in children. In a prospective, interventional, non-randomized case series, three patients (three eyes) aged 16, seven and two years were diagnosed to have Coats' disease. In Case 1 (16 yr/ male) with macular edema, previous laser photocoagulation being unsuccessful, intravitreal pegaptanib sodium (Macugen™) was tried. Case 2 (seven yr/ male) and Case 3 (two yr/ female) were diagnosed to have Stage 4 Coats' and underwent external needle drainage, laser photocoagulation, SF6 gas injection and intravitreal injection of bevacizumab (Avastin™). Reduction of exudation and attached posterior pole (Cases 2 and 3) was seen at a follow-up of six months and two months respectively. Intravitreal anti-VEGF agents may be successfully used as adjunct treatment in select cases of Coats' disease in childhood. |
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