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Year : 2014  |  Volume : 62  |  Issue : 3  |  Page : 337-339

A rare case of toxic optic neuropathy secondary to consumption of neem oil

Department of Ophthalmology, J. J. M. Medical College, Davangere, Karnataka, India

Correspondence Address:
A R Suresha
Pavan Sadan, No. 2603/12, 2nd Cross, MCC A Block Davangere, Karnataka 577 004
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0301-4738.121129

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A 35-year-old female was referred to our hospital with bilateral loss of vision of two days duration. She gave history of consumption of about 150 ml of neem oil five days back.Examination revealed no perception of light in both eyes. Both pupils were dilated and sluggishly reacting to light. Her fundus examination showed bilateral hyperemic, edematous discs and also edema extending along the superior and inferior temporal vascular arcade. Magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted, images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia. Her vision improved to 20/200 in both eyes with treatment after two months. This is the first case report of such nature in the literature to the best of our knowledge.

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