| BRIEF COMMUNICATION |
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| Year : 2016 | Volume
: 64
| Issue : 8 | Page : 601-603 |
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IgG4-related intraocular inflammation masquerading as ciliary body melanoma in a young girl
Dipankar Das1, Panna Deka1, Geeta Verma2, Ganesh Chandra Kuri3, Harsha Bhattacharjee3, Gayatri Bharali3, Divya Pandey3, Akanksha Koul3, Bidisha Das3, Apurba Deka1
1 Department of Ocular Pathology, Sri Sankaradeva Nethralaya, Guwahati, Assam, India
2 SRL, Mumbai, Maharashtra, India
3 Sri Sankaradeva Nethralaya, Guwahati, Assam, India
Correspondence Address:
Dr. Dipankar Das
Department of Ocular Pathology, Uveitis and Neuro-Ophthalmology Services, Sri Sankaradeva Nethralaya, Guwahati - 781 028, Assam
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0301-4738.191510
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Immunoglobulin G4 (IgG4-related diseases) affects various tissues and organs of the human body. Orbital, adnexal, and scleral inflammations were already reported in the medical literature. To the best of our knowledge, we report the first case of intraocular IgG4-associated inflammatory mass in the ciliary body mimicking as a melanoma in a 23-year-old female from Northeast India. Characteristic histopathology, immunohistochemistry in the tissue, protein chemistry, and raised serum IgG4 were supportive for the diagnosis. As this newly diagnosed disease has multi-organ affection and little is known about its pathogenesis particularly in eye and adnexa, the present case will open many challenges in clinico-pathological diagnosis and research in the future. |
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