Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules
Sima Das1, Sweety Tiple1, Julie Pegu2, Suneeta Dubey2, Umang Mathur3, Kaustabh Mulay4, Carol L Shields5
1 Department of Oculoplasty and Ocular Oncology Services, Dr Shroff's Charity Eye Hospital, New Delhi, India 2 Glaucoma Services, Dr Shroff's Charity Eye Hospital, New Delhi, India 3 Cornea and Anterior Segment, Dr Shroff's Charity Eye Hospital, New Delhi, India 4 National Reporting Centre for Ophthalmic Pathology, Centre for Sight, Hyderabad, Telangana, India 5 Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, Philadelphia, PA, USA
Correspondence Address:
Dr. Sima Das 128 Ankur Apartments, 7 I P Extension, Patparganj, New Delhi - 110 092 India
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/ijo.IJO_812_19
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Ocular amylodosis, although a rare entity, is known to affect the conjunctiva, extraocular muscles, orbit, lacrimal gland, and skin around the eyes. Intraocular deposition of amyloid mainly confines to the vitreous and cornea. In this report, we describe two cases of intraocular amyloidosis presenting as multiple iris and anterior chamber cysts. Histopathological examination with special stain like Congo Red and Transmission Electron Microscopy confirmed the diagnosis of amyloidosis. Systemic investigations ruled out systemic association confirming the diagnosis of primary ocular amyloidosis.
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