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| LETTER TO THE EDITOR |
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| Year : 2019 | Volume
: 67
| Issue : 8 | Page : 1382-1383 |
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Feasibility and outcome of simple limbal epithelial transplantation (SLET) in unilateral total limbal stem cell deficiency (LSCD) following chemical injury, in a semiurban location in Western India
Sushmita G Shah1, Shreya M Shah2, Juhee Agarwal2, Ankita Mulchandani2
1 Cornea and Anterior Segment Services, Drashti Nethralaya, Dahod, Gujarat; Eye Life; Netra Mandir, Mumbai, Maharashtra, India
2 Cornea and Anterior Segment Services, Drashti Nethralaya, Dahod, Gujarat, India
| Date of Web Publication | 22-Jul-2019 |
Correspondence Address:
Dr. Sushmita G Shah
Eye Life, 204 Ram Krishna Chambers, Liking Road, Khar West, Mumbai – 52
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijo.IJO_1697_18
How to cite this article:
Shah SG, Shah SM, Agarwal J, Mulchandani A. Feasibility and outcome of simple limbal epithelial transplantation (SLET) in unilateral total limbal stem cell deficiency (LSCD) following chemical injury, in a semiurban location in Western India. Indian J Ophthalmol 2019;67:1382-3 |
How to cite this URL:
Shah SG, Shah SM, Agarwal J, Mulchandani A. Feasibility and outcome of simple limbal epithelial transplantation (SLET) in unilateral total limbal stem cell deficiency (LSCD) following chemical injury, in a semiurban location in Western India. Indian J Ophthalmol [serial online] 2019 [cited 2023 Mar 22];67:1382-3. Available from: https://journals.lww.com/ijo/pages/default.aspx/text.asp?2019/67/8/1382/263118 |
Sir,
Simple limbal epithelial transplantation (SLET) was first described by Sangwan et al. as an innovative technique for the management of unilateral total limbal stem cell deficiency (LSCD).[1] Subsequently, its efficacy has been described by Vazirani et al. in a multicenter study conducted across advanced eye care centers in urban locations in India, United States, and Mexico.[2]
We describe the outcome and feasibility of performing SLET by a trained corneal surgeon in a semi-urban setting in western India. Patients with unilateral total LSCD following chemical injury with healthy fellow eye were included. Surgical technique as described by Sangwan et al. was followed.[1] Outcome measures were as follows: (i) Improvement in visual acuity, (ii) improvement in corneal clarity and LSCD, (iii) ease of performing SLET in a semi-urban setting.
Three patients, two males and one female with age range 13-16 years were included in the study. One patient had history of lime burn while two had exposure to unknown chemicals. At mean follow up of 4.33 months (range 2-6 months), two patients (66.6%) improved from preoperative visual acuity of <20/400 to 20/80 and 20/60, respectively. One patient remained at 20/400 which could be attributed to pre-existing amblyopia. Complete resolution of LSCD was noted in two patients (66.6%) while one patient had localized residual pannus of 1 clock hour.
Our results are comparable to that of the multicenter study.[2] As mentioned by Basu et al., the advantages of SLET include minimal surgical paraphernalia, logistical support, and training.[3] In our study, the procedures were easily performed by an experienced cornea specialist who had attended SLET workshops and had performed a few cases of SLET prior to this study. The other essential requirements include fresh frozen amniotic membrane and fibrin glue which can be made available even in semi-urban areas. SLET can thus be performed in hospitals located in such areas.
To conclude, this study establishes that SLET could be performed by a trained corneal surgeon even in semi-urban settings with useful outcomes.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
| References | |  |
| 1. | Sangwan VS, Basu S, MacNeil S, Balasubramanian D. Simple limbal epithelial transplantation (SLET): A novel surgical technique for the treatment of unilateral limbal stem cell deficiency. Br J Ophthalmol 2012;96:931-4.  |
| 2. | Vazirani J, Ali MH, Sharma N, Gupta N, Mittal V, Atallah M, et al. Autologous simple limbal epithelial transplantation for unilateral limbal stem cell deficiency: Multicentre results. Br J Ophthalmol 2016;100:1416-20. |
| 3. | Basu S, Bahuguna C, Singh V. Simple limbal epithelial transplantation: Impactful innovation. Ind J Ophthalmol 2018;66:53-4. |
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