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OPHTHALMIC IMAGE
Year : 2020  |  Volume : 68  |  Issue : 11  |  Page : 2524

In-vivo and ex-vivo analysis of an unusual case of huge bullous keratopathy


Department of Ophthalmology, University Magna Graecia of Catanzaro, Catanzaro, Italy

Date of Web Publication26-Oct-2020

Correspondence Address:
Prof. Giuseppe Giannaccare
Viale Europa, 88100, Germaneto, Catanzaro
Italy
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_1085_20

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How to cite this article:
Giannaccare G, Lucisano A, Scorcia V. In-vivo and ex-vivo analysis of an unusual case of huge bullous keratopathy. Indian J Ophthalmol 2020;68:2524

How to cite this URL:
Giannaccare G, Lucisano A, Scorcia V. In-vivo and ex-vivo analysis of an unusual case of huge bullous keratopathy. Indian J Ophthalmol [serial online] 2020 [cited 2020 Nov 25];68:2524. Available from: https://www.ijo.in/text.asp?2020/68/11/2524/299012



A 72-year-old woman presented with painful corneal edema in an eye blinded by angle-closure glaucoma. Slit-lamp examination showed the anterior corneal surface protruding through the palpebral fissure (A-B) [Figure 1]. Anterior segment optical coherence tomography (AS-OCT) revealed the presence of an unusual huge epithelial bulla delimiting two virtual spaces (”clefts”) (C). The bullous lesion was surgically removed and Gundersen conjunctival flap was used to resurface the underlying fibrous pannus.[1] Histologically, the two clefts originated from the splitting of the corneal epithelium (D).
Figure 1: Slit lamp examination showed a huge epithelial bulla of the cornea protruding through the palpebral fissure (a and b). Anterior segment OCT revealed two “clefts” that originated from the splitting of the corneal epithelium, as confirmed by histopathology (c and d)

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This unique case highlights the importance of AS-OCT for surgical planning and histopathology for a definitive diagnosis.

Acknowledgments

The authors would like to thank the Veneto Eye Bank Foundation (Venice, Italy) for conducting the histological analysis of the specimen.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Conjunctival flaps in the treatment of corneal disease with reference to a new technique of application. AMA Arch Ophthalmol 1958;60:880-8.  Back to cited text no. 1
    


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