|Year : 2020 | Volume
| Issue : 11 | Page : 2531
Multiplexed optical coherence tomography imaging of optic disc drusen
Isabelle Karlesand1, Anne-Sofie Wessel Lindberg2, Lasse Malmqvist1, Lea Lybek Rueløkke1, Steffen Hamann1
1 Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Glostrup, Denmark
2 Department of Applied Mathematics and Computer Science, Technical University of Denmark, Kgs, Lyngby, Denmark
|Date of Web Publication||26-Oct-2020|
Dr. Isabelle Karlesand
Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Valdemar Hansens Vej 1-23, Glostrup
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Karlesand I, Lindberg AS, Malmqvist L, Rueløkke LL, Hamann S. Multiplexed optical coherence tomography imaging of optic disc drusen. Indian J Ophthalmol 2020;68:2531
|How to cite this URL:|
Karlesand I, Lindberg AS, Malmqvist L, Rueløkke LL, Hamann S. Multiplexed optical coherence tomography imaging of optic disc drusen. Indian J Ophthalmol [serial online] 2020 [cited 2020 Nov 27];68:2531. Available from: https://www.ijo.in/text.asp?2020/68/11/2531/299096
Optic disc drusen (ODD) are calcified masses in the prelaminar optic nerve head seen in up to 2% of the population. Although the pathophysiology is not fully understood, altered microvascularization could both be part of the pathogenesis and a consequence of ODD. We developed a method that combines information from optical coherence tomography (OCT) angiography regarding peripapillary vessel density along with information from enhanced depth imaging OCT about anatomical ODD location and volume [Figure 1]. In this patient, the majority of the ODD volume is located nasally and in the adjacent peripapillary section wherein the vessel density is correspondingly lower.
|Figure 1: (a) Fundus photo of the left optic disc with visible ODD. (b) Corresponding en face OCT angiogram where the peripapillary region is divided into 6 Garway-Heath map sections. Each violet shade represents the vessel density within the section. The volume and location of the ODD is represented as a height map using a blue-red color scale. (c) Enhanced depth imaging OCT shows a characteristic hyporeflective structure with a hyperreflective rim consistent with ODD. (d) The segmented ODD is colored blue|
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| References|| |
Hamann S, Malmqvist L, Costello F. Optic disc drusen: Understanding an old problem from a new perspective. Acta Ophthalmol 2018;96:673-84.