CASE REPORT |
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Year : 2020 | Volume
: 68
| Issue : 9 | Page : 2002-2003 |
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Zoledronic acid induced unilateral anterior uveitis
Shipra Gupta1, Abhishek Onkar1, Tushar Vashisht2
1 Department of Ophthalmology, G.B. Pant Hospital, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar, India 2 Department of Pharmacology, G.B. Pant Hospital, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar, India
Correspondence Address:
Dr. Abhishek Onkar Department of Ophthalmology, Andaman and Nicobar Islands Institute of Medical Sciences, Room No. 31, G.B. Pant Hospital, Atlanta Point, Port Blair - 744 104, Andaman and Nicobar India
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/ijo.IJO_1654_19
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Zoledronic acid is recommended for patients with osteoporosis. To report a case of unilateral anterior uveitis after zoledronate infusion. An osteoporotic patient presented with pain, visual loss, hyperemia, photophobia, and watering from the left eye after zoledronate infusion. Circumcorneal injection, keratic precipitates, cells, and flare suggested anterior uveitis. Her symptoms resolved completely after 20 days of prednisolone acetate with atropine eye drops. Uveitis is a rare complication of zoledronic acid with an unclear mechanism. Proinflammatory cytokines may play a role in pathogenesis. Zoledronic acid may be associated with rare but serious inflammatory ocular adverse drug reactions.
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