Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 1525
  • Home
  • Print this page
  • Email this page

   Table of Contents      
LETTER TO THE EDITOR
Year : 2021  |  Volume : 69  |  Issue : 1  |  Page : 169

Comments on: Glycerol-preserved corneal tissue in emergency corneal transplantation: An alternative for fresh corneal tissue in COVID-19 crisis


Department of Ophthalmology, All India Institute of Medical Sciences, Bathinda, Punjab, India

Date of Web Publication15-Dec-2020

Correspondence Address:
Dr. Anuradha Raj
Department of Ophthalmology, All India Institute of Medical Sciences, Bathinda - 151 001, Punjab
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_2223_20

Rights and Permissions

How to cite this article:
Raj A, Agrawal N. Comments on: Glycerol-preserved corneal tissue in emergency corneal transplantation: An alternative for fresh corneal tissue in COVID-19 crisis. Indian J Ophthalmol 2021;69:169

How to cite this URL:
Raj A, Agrawal N. Comments on: Glycerol-preserved corneal tissue in emergency corneal transplantation: An alternative for fresh corneal tissue in COVID-19 crisis. Indian J Ophthalmol [serial online] 2021 [cited 2021 Jan 21];69:169. Available from: https://www.ijo.in/text.asp?2021/69/1/169/303294



Dear Editor;

We read the article by Gupta et al. on “Glycerol-preserved corneal tissue in emergency corneal transplantation: An alternative for fresh corneal tissue in COVID-19 crisis”[1] with profound interest and want to congratulate the authors for their research work. Glycerol-preserved cornea (GPC) has important utility in emergency keratoplasty where the availability of fresh corneal tissue (FCT) is questionable in the developing world.[2] We would like to appreciate the authors for comparing the GPC and FCT in corneal transplantations. However, we would like to draw attention to clarify our concerns regarding this published article.

First of all the title of the article in unjustified as the data presented in the study does not belong to the COVID era. The whole article is not explaining anything related to the COVID era, but just a paragraph at the end cannot justify the article title. To make a statement in the title, the data should be around that time domain.

The next point lies in statistical analysis as this section mentioned about Mann-Whitney U test, t-test, and Chi-square test. However, [Table 4] uses Fisher's exact test, which is not mentioned in the methodology.[1]

In the result section, it is mentioned that there was 100% graft failure in glycerol-preserved tissue. We believe that it is worth to classify graft failure in terms of primary graft failure and secondary graft failure. The authors have described retransplanting with optical grade tissues in 11 eyes in the FCT group and 5 eyes in the GPC group, but the GPC group showed graft failure in all 34 cases. The fate of the other 29 cases of graft failure is not mentioned. Besides, the authors mentioned that there was a reinfection in 11 eyes in the FCT group. It would have been informative if the management of graft infection was mentioned in terms of conservative or surgical.

Furthermore, there is repetition and duplication of data of the GPC group mentioned in results, in [Table 2] and [Table 3] and [Table 4] with a previous article published in 2017 in IJO with PMID 28724812.[3] Publishing or reusing the same dataset is considered as an overlapping publication or salami slicing.[4] In our opinion, duplication of data is wrong on ethical grounds if it is used for the same purpose for different titles.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Gupta N, Dhasmana R, Maitreya A, Badahur H. Glycerol-preserved corneal tissue in emergency corneal transplantation: An alternative for fresh corneal tissue in COVID-19 crisis. Indian J Ophthalmol 2020;68:1412-6.  Back to cited text no. 1
[PUBMED]  [Full text]  
2.
Michael RF, Geoffrey CT, Lloyd W, Matt O. The use of glycerol-preserved corneas in the developing world. Middle East Afr J Ophthalmol 2010;17:38-43.  Back to cited text no. 2
    
3.
Gupta N, Upadhyay P. Use of glycerol-preserved corneas for corneal transplants. Indian J Ophthalmol 2017;65:569-73.  Back to cited text no. 3
[PUBMED]  [Full text]  
4.
Sarwar U, Nicolaou M. Fraud and deceit in medical research. J Res Med Sci 2012;17:1077-81.  Back to cited text no. 4
    




 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
References

 Article Access Statistics
    Viewed250    
    Printed2    
    Emailed0    
    PDF Downloaded30    
    Comments [Add]    

Recommend this journal