%A Verma, V
%A Kumar, Sanjeev
%A Kumar, Arun
%A Anand, Ravi
%T The Effect of Lignocaine and Metoclopramide Alone and in Combination on Pain after Propofol Intravenous Injection in Adult Surgical Patients Scheduled for Elective Surgery Under General Anaesthesia: A Prospective, Double Blind, Randomized Clinical Study
%9 Original Article
%D 1990
%J Indian Journal of Ophthalmology
%P 14-16
%V 38
%N 1
%U https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=1990;volume=38;issue=1;spage=14;epage=16;aulast=Verma
%8 January 1, 1990
%X
Introduction: Propofol causes pain on injection in 28% - 90% of patients. A number of techniques have been tried for minimizing propofol induced pain with variable results.
Objectives: To compare the use of lignocaine, metoclopramide and metoclopramide &lignocaine combination for the reduction of pain during injection of propofol in adult patients. Design: A prospective, double blind, randomized study.
Setting: Department of Anaesthesiology and Critical Care Medicine, Indira Gandhi Institute of Medical Sciences, Patna Period: From June 2007 to March 2008
Materials & Methods: 150 subjects (ASA I-II) scheduled for elective operations under general anaesthesia were allocated into three groups and treated as follows: Group A:40mg lignocaine 2%(2ml) and 2ml normal saline; Group B: 10 mg metoclopramide(2ml) and 2ml normal saline ,Group C 40mg lignocaine 2% &: 10 mg metoclopramide. Pain intensity was graded by a single blinded observer and recorded as either severe, moderate, mild or no pain according to the response of the patients to the injection.
Results: The incidence of pain was 46% in metoclopramide group compared to 26% in the lignocaine and 12% in the lignocaine& metoclopramide group.
Conclusion: lignocaine & metoclopramide combination is more effective than metoclopramide and lignocaine alone in decreasingthe pain of propofol injection.
%0 Journal Article
%I Wolters Kluwer Medknow Publications
%@ 0301-4738