TY - JOUR A1 - Kalariya, N A1 - Rawal, U A1 - Vasavada, A T1 - Human lens epithelial layer in cortical cataract Y1 - 1998/7/1 JF - Indian Journal of Ophthalmology JO - Indian J Ophthalmol SP - 159 EP - 162 VL - 46 IS - 3 UR - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=1998;volume=46;issue=3;spage=159;epage=162;aulast=Kalariya N2 - Normal and cataractous human eye lenses were studied by morphology and protein analysis. A marked decrease in protein sulfhydryl (PSH) and nonprotein sulfhydryl (NSPH) was observed in nuclear and cortical cataractous epithelia. Moreover, decrease in PSH contents and an increase in insoluble proteins were found to be correlated only in cortical cataractous epithelium which is also accompanied by various morphological abnormalities. In nuclear cataractous epithelium, however, there was very little insolubilisation of proteins. The epithelial morphology in nuclear cataracts was almost similar to normal lens epithelium. Hence, it is assumed that the protein insolubilisation and various morphological abnormalities are characteristics of cortical cataractous epithelium. This leads us to believe that opacification in cortical cataract might initiate in the epithelial layer. ER -