%A Narang, S
%A Gupta, V
%A Gupta, A
%A Dogra, Mangat
%A Pandav, Surinder
%A Das, S
%T Role of prophylactic intravitreal antibiotics in open globe injuries.
%9 Original Article
%D 2003
%J Indian Journal of Ophthalmology
%P 39-44
%V 51
%N 1
%U https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2003;volume=51;issue=1;spage=39;epage=44;aulast=Narang
%8 January 1, 2003
%X Purpose: To determine the efficacy of prophylactic intravitreal antibiotics in reducing the incidence of endophthalmitis after trauma.
Methods: This was a prospective, randomised, case control study of 70 consecutive patients with open globe injury. The patients were prospectively randomised into group I (32 eyes) and group II (38 eyes). Group I patients were given prophylactic intravitreal injection of vancomycin 1 mg and ceftazidime 2.25 mg at the conclusion of primary repair. Group II patients were not given prophylactic intravitreal antibiotics. All the patients received intravenous ciprofloxacin.
Results: The incidence of endophthalmitis was higher in group II (7 of 38 eyes; 18.42%) compared to group I (2 of 32 eyes; 6.25%). Both the patients who developed endophthalmitis despite prophylactic intravitreal antibiotics in group I had an initially undetected intraocular foreign body (eyelash) in the vitreous cavity.
Conclusions: Prophylactic intravitreal broad spectrum antibiotic injection decreases the risk of post-traumatic endophthalmitis.
%0 Journal Article
%I Wolters Kluwer Medknow Publications
%@ 0301-4738