TY - JOUR A1 - Kenawy, Nihal A1 - Pilz, Daniela A1 - Watts, Patrick T1 - Familial unilateral Brown syndrome Y1 - 2008/9/1 JF - Indian Journal of Ophthalmology JO - Indian J Ophthalmol SP - 430 EP - 434 VL - 56 IS - 5 UR - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2008;volume=56;issue=5;spage=430;epage=434;aulast=Kenawy DO - 10.4103/0301-4738.42427 N2 - We present a two-generation family with Brown syndrome. The proband was a six and a half-year-old female who presented with a history of failure of dextro-elevation of her left eye. A full ophthalmic evaluation was consistent with a left Brown syndrome. Family history revealed that her mother was operated on as a child for left Brown syndrome and examination of her four and a half-year-old sibling showed similar affection in the left eye. Autosomal dominant inheritance has been postulated in this condition. To our knowledge this is the first report of three members of a two-generation family with left-sided Brown syndrome. Genetic counseling of Brown syndrome cases is advised; nevertheless, identification of the responsible gene should shed more light on its genetics. ER -