%A Zaky, Khaled %A Khalifa, Yasser %T Efficacy of preoperative injection versus intraoperative application of mitomycin in recurrent pterygium surgery %9 Original Article %D 2012 %J Indian Journal of Ophthalmology %R 10.4103/0301-4738.98703 %P 273-276 %V 60 %N 4 %U https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2012;volume=60;issue=4;spage=273;epage=276;aulast=Zaky %8 July 1, 2012 %X Purpose: To determine the efficacy of preoperative subconjunctival injection of mitomycin C a day before surgery in the management of recurrent pterygium. Materials and Methods: Randomized comparative case series. Fifty eyes with recurrent pterygium were randomly divided into two groups; the mitomycin injection group (25 eyes) and the mitomycin application group (25 eyes). The mitomycin injection group underwent preoperative subconjunctival injection of mitomycin C in low dose (0.1 ml of 0.15 mg/ml) a day before bare sclera pterygium excision surgery. The mitomycin application group underwent bare sclera pterygium excision with topical application of mitomycin C (same concentration). Results: At one year of follow-up, 24 of 25 eyes (96%) in the mitomycin injection group and 23 of 25 (92%) eyes in the mitomycin application group were free of recurrence. The difference was statistically insignificant. As regards postoperative complications, delayed epithelization (more than two weeks) occurred in two eyes (8%) in the mitomycin injection group and in one eye (4%) in the mitomycin application group. Scleral thinning was reported in one eye (4%) in the mitomycin application group which resolved within three weeks after surgery, no other serious postoperative complications were reported. Conclusion: Preoperative subconjunctival injection of mitomycin C in low dose (0.1 ml of 0.15 mg/ml) a day before pterygium surgery is a simple and effective modality for management of recurrent pterygium. It has the advantage of low recurrence and complications' rate. %0 Journal Article %I Wolters Kluwer Medknow Publications %@ 0301-4738