AU - Agrawal, Deepika AU - Bhake, Arvind AU - Rastogi, Naincy AU - Laishram, Sheronica AU - Wankhade, Akanksha AU - Agarwal, A TI - Role of Bethesda system for reporting thyroid lesion and its correlation with histopathological diagnosis PT - ORIG DP - 2014 Apr 1 TA - Indian Journal of Ophthalmology PG - 74-81 VI - 62 IP - 1 4099- https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2014;volume=62;issue=1;spage=74;epage=81;aulast=Agrawal;type=0 4100- https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2014;volume=62;issue=1;spage=74;epage=81;aulast=Agrawal AB - Introduction: Interestingly enough, while TBS is forging ahead to bring about uniformity a thyroid FNA cytology reporting, a similar milestone has also been reported with an application of United Kingdom (UK-RC path system or BTA/RC Path) for reporting thyroid FNA cytology. It achieved practicing activism in 2003 and later got modified in the year 2009 & 2016. The TBS and RC path system being contemporary system of reporting thyroid cytopathology, uniform system of reporting cytopathology of nodular thyroid lesion still is not achieved but activated. Aim: To study the nodular thyroid lesions on FNAC by reporting system of TBSRTC and UK RC Path. Objectives: To compare the categories of the Bethesda system with contemporary categories of UK Royal college of pathologist for cytomorphological diagnosis and overlaps as well as with conventional reporting system and to compare with tissue diagnosis of surgically resected specimen of nodular thyroid lesions for its malignancy risk. Material and Methods: This study is hospital-based observational prospective and analytic study including 255 patients with nodular thyroid lesion. FNAC were carried out with or without under the guidance of sonography. The staining performed were conventional for smears of the aspirate. The smears were classified and categorized by two systems, TBSRTC and UK-RC path system of reporting thyroid lesion. The tissue diagnosis was done for the surgically resected specimens of nodular thyroid lesion in case of patient who underwent surgery. The values of comparative statistics were bought out. Observations: Females predominated over males. The distribution of cases for into the categories of TBSRTC and UK RC Path were as follow: category I/Thy1- 23, category II/Thy2-156, category III/Thy 3a-21/19, category IV/Thy3f-22/24, category V/Thy4-21, category VI/Thy5-16. There were 57 patients underwent surgical intervention in form of total or partial thyroidectomy or lobectomy and had available histopathological examination reports for cyto-histopathology co-relation. Values of comparative analysis show high NPV, PPV and high values of specificity, as compared to conventional. Conclusion: TBSRTC and UK RC path for reporting thyroid cytology are suitable for reporting thyroid nodular lesions on FNAC because of uniformity of nomenclature categories and implication at management with high correlation percentile with subsequent surgically resected specimen of thyroid.